Krüppel-like factor 4 (KLF4) is an evolutionarily conserved zinc finger-containing
transcription factor that regulates diverse cellular processes such as cell growth …

Glutathione S-transferases (GSTs) are phase II detoxifying enzymes involved in the
maintenance of cell integrity, oxidative stress and protection against DNA damage by …

Multifunctional enzymes glutathione transferases (GSTs) are involved in the development of
chemoresistance, thus representing a promising target for a novel approach in cancer …

Nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) is a transcription factor which regulates
the expression of many cytoprotective genes. In the present study, we found that the …

Epigenetic deregulation of gene expression has a role in the initiation and progression of
prostate cancer (PCa). The histone methyltransferase MMSET/WHSC1 (Multiple Myeloma …

BACKGROUND Prostate cancer has been reported to occur more commonly in neutered
than intact male dogs in several case series. This study was undertaken to evaluate risk of …

Epigenetic aberrations and cancer | Molecular Cancer Skip to main content SpringerLink
Account Menu Find a journal Publish with us Track your research Search Cart 1.Home 2.Molecular …

Purpose: Prostate cancer is a leading cause of cancer death among the aging male
population but the mechanism underlying this association is unclear. Aberrant methylation of …

Background ETS transcription factors regulate important signaling pathways involved in cell
differentiation and development in many tissues and have emerged as important players in …

Epigenetic programming of the germ line occurs during embryonic development in a sex-
specific manner. The male germ line becomes imprinted following sex determination …