Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook
The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …
dye with high structural tailorability is of great significance in the field of detection …
[HTML][HTML] Targeting cancer stem cell pathways for cancer therapy
L Yang, P Shi, G Zhao, J Xu, W Peng, J Zhang… - Signal transduction and …, 2020 - nature.com
Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …
[HTML][HTML] Biomarkers in stress related diseases/disorders: diagnostic, prognostic, and therapeutic values
Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …
organisms at the molecular to the whole-body level, inducing the so-called state of stress …
JCS/CVIT/JCC 2023 guideline focused update on diagnosis and treatment of vasospastic angina (coronary spastic angina) and coronary microvascular dysfunction
S Hokimoto, K Kaikita, S Yasuda, K Tsujita… - Circulation …, 2023 - jstage.jst.go.jp
In 2008, the Guidelines for diagnosis and treatment of patients with vasospastic angina
(coronary spastic angina) 1 were developed by the Japanese Circulation Society, and the …
(coronary spastic angina) 1 were developed by the Japanese Circulation Society, and the …
Aldehyde dehydrogenases: not just markers, but functional regulators of stem cells
G Vassalli - Stem cells international, 2019 - Wiley Online Library
Aldehyde dehydrogenase (ALDH) is a superfamily of enzymes that detoxify a variety of
endogenous and exogenous aldehydes and are required for the biosynthesis of retinoic …
endogenous and exogenous aldehydes and are required for the biosynthesis of retinoic …
Varieties, production, composition and health benefits of vinegars: A review
Vinegars are liquid products produced from the alcoholic and subsequent acetous
fermentation of carbohydrate sources. They have been used as remedies in many cultures …
fermentation of carbohydrate sources. They have been used as remedies in many cultures …
[HTML][HTML] Insights into aldehyde dehydrogenase enzymes: a structural perspective
Aldehyde dehydrogenases engage in many cellular functions, however their dysfunction
resulting in accumulation of their substrates can be cytotoxic. ALDHs are responsible for the …
resulting in accumulation of their substrates can be cytotoxic. ALDHs are responsible for the …
Breast cancer stem cells, heterogeneity, targeting therapies and therapeutic implications
X Zeng, C Liu, J Yao, H Wan, G Wan, Y Li… - Pharmacological …, 2021 - Elsevier
Both hereditary and sporadic breast cancer are suggested to develop from a stem cell
subcomponent retaining most key stem cell properties but with dysregulation of self-renewal …
subcomponent retaining most key stem cell properties but with dysregulation of self-renewal …
A role for cancer stem cells in therapy resistance: cellular and molecular mechanisms
M Cojoc, K Mäbert, MH Muders, A Dubrovska - Seminars in cancer biology, 2015 - Elsevier
Similar to normal tissue, many tumors have a hierarchical organization where tumorigenic
cancer stem cells (CSCs) differentiate into non-tumorigenic progenies. A host of studies …
cancer stem cells (CSCs) differentiate into non-tumorigenic progenies. A host of studies …
Noninvasive diagnosis of gastric cancer based on breath analysis with a tubular surface-enhanced Raman scattering sensor
SERS-based breath analysis as an emerging technique has attracted increasing attention in
cancer screening. Here, eight aldehydes and ketones in the human breath are reported as …
cancer screening. Here, eight aldehydes and ketones in the human breath are reported as …