Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook

H Li, H Kim, F Xu, J Han, Q Yao, J Wang, K Pu… - Chemical Society …, 2022 - pubs.rsc.org
The discovery of a near-infrared (NIR, 650–900 nm) fluorescent chromophore hemicyanine
dye with high structural tailorability is of great significance in the field of detection …

[HTML][HTML] Targeting cancer stem cell pathways for cancer therapy

L Yang, P Shi, G Zhao, J Xu, W Peng, J Zhang… - Signal transduction and …, 2020 - nature.com
Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …

[HTML][HTML] Biomarkers in stress related diseases/disorders: diagnostic, prognostic, and therapeutic values

K Dhama, SK Latheef, M Dadar, HA Samad… - Frontiers in molecular …, 2019 - frontiersin.org
Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

JCS/CVIT/JCC 2023 guideline focused update on diagnosis and treatment of vasospastic angina (coronary spastic angina) and coronary microvascular dysfunction

S Hokimoto, K Kaikita, S Yasuda, K Tsujita… - Circulation …, 2023 - jstage.jst.go.jp
In 2008, the Guidelines for diagnosis and treatment of patients with vasospastic angina
(coronary spastic angina) 1 were developed by the Japanese Circulation Society, and the …

Aldehyde dehydrogenases: not just markers, but functional regulators of stem cells

G Vassalli - Stem cells international, 2019 - Wiley Online Library
Aldehyde dehydrogenase (ALDH) is a superfamily of enzymes that detoxify a variety of
endogenous and exogenous aldehydes and are required for the biosynthesis of retinoic …

Varieties, production, composition and health benefits of vinegars: A review

CW Ho, AM Lazim, S Fazry, UKHH Zaki, SJ Lim - Food chemistry, 2017 - Elsevier
Vinegars are liquid products produced from the alcoholic and subsequent acetous
fermentation of carbohydrate sources. They have been used as remedies in many cultures …

[HTML][HTML] Insights into aldehyde dehydrogenase enzymes: a structural perspective

K Shortall, A Djeghader, E Magner… - Frontiers in Molecular …, 2021 - frontiersin.org
Aldehyde dehydrogenases engage in many cellular functions, however their dysfunction
resulting in accumulation of their substrates can be cytotoxic. ALDHs are responsible for the …

Breast cancer stem cells, heterogeneity, targeting therapies and therapeutic implications

X Zeng, C Liu, J Yao, H Wan, G Wan, Y Li… - Pharmacological …, 2021 - Elsevier
Both hereditary and sporadic breast cancer are suggested to develop from a stem cell
subcomponent retaining most key stem cell properties but with dysregulation of self-renewal …

A role for cancer stem cells in therapy resistance: cellular and molecular mechanisms

M Cojoc, K Mäbert, MH Muders, A Dubrovska - Seminars in cancer biology, 2015 - Elsevier
Similar to normal tissue, many tumors have a hierarchical organization where tumorigenic
cancer stem cells (CSCs) differentiate into non-tumorigenic progenies. A host of studies …

Noninvasive diagnosis of gastric cancer based on breath analysis with a tubular surface-enhanced Raman scattering sensor

L Huang, Y Zhu, C Xu, Y Cai, Y Yi, K Li, X Ren… - ACS …, 2022 - ACS Publications
SERS-based breath analysis as an emerging technique has attracted increasing attention in
cancer screening. Here, eight aldehydes and ketones in the human breath are reported as …