Alcohol-associated liver disease (ALD) comprises a spectrum of liver diseases that include:
steatosis to alcohol-associated hepatitis, cirrhosis, and ultimately hepatocellular carcinoma …

The innate system constitutes a first-line defence mechanism against pathogens. 80% of the
blood supply entering the human liver arrives from the splanchnic circulation through the …

Alcohol use is known to alter the function of both innate and adaptive immune cells, such as
neutrophils, macrophages, B cells, and T cells. Immune dysfunction has been associated …

Alcohol use disorder (AUD) remains a significant public health concern, affecting around 5%
of adults worldwide. Novel pathways of damage have been described during the last years …

Mammalian innate-like T cells (ILTCs), including mucosal-associated invariant T (MAIT),
natural killer T (NKT), and γδ T cells, are abundant tissue-resident lymphocytes that have …

Background and aims Mucosal‐associated invariant T (MAIT) cells are innate‐like
lymphocytes that display a critical role in various liver diseases. However, the role of MAIT …

Alcohol-related liver disease (ALD), which is caused by excessive alcohol consumption, is
one of the most common types of liver disease and a primary cause of hepatic injury, with a …

Mucosal-associated invariant T (MAIT) cells are a subset of innate-like T cells that regulate
the immune response via rapidly releasing inflammatory factors, including during …

Background and aims Infection is a serious complication in patients with cirrhosis. Mucosal-
associated invariant T (MAIT) cells are involved in the immune defense against infections …

Background: Mucosal-associated invariant T cells (MAITs) are markedly reduced in patients
with alcohol-associated liver disease (ALD); however, the potential mechanism underlying …