Perivascular adipose tissue (PVAT) in atherosclerosis: a double-edged sword
XY Qi, SL Qu, WH Xiong, O Rom, L Chang… - Cardiovascular …, 2018 - Springer
Perivascular adipose tissue (PVAT), the adipose tissue that surrounds most of the
vasculature, has emerged as an active component of the blood vessel wall regulating …
vasculature, has emerged as an active component of the blood vessel wall regulating …
Dietary antiaging phytochemicals and mechanisms associated with prolonged survival
Aging is well-known an inevitable process that is influenced by genetic, lifestyle and
environmental factors. However, the exact mechanisms underlying the aging process are …
environmental factors. However, the exact mechanisms underlying the aging process are …
C1q/TNF-related proteins, a family of novel adipokines, induce vascular relaxation through the adiponectin receptor-1/AMPK/eNOS/nitric oxide signaling pathway
Q Zheng, Y Yuan, W Yi, WB Lau, Y Wang… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—Reduced plasma adiponectin (APN) in diabetic patients is associated with
endothelial dysfunction. However, APN knockout animals manifest modest systemic …
endothelial dysfunction. However, APN knockout animals manifest modest systemic …
Clinical Spectrum of PRKAG2 Syndrome
AG Porto, F Brun, GM Severini, P Losurdo… - Circulation …, 2016 - Am Heart Assoc
Materials and Methods A search of the English literature was performed using PubMed up to
September 2014 on the clinical features, genetics, and pathophysiology of PS syndrome …
September 2014 on the clinical features, genetics, and pathophysiology of PS syndrome …
Regulation of NAD (P) H oxidases by AMPK in cardiovascular systems
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are ubiquitously
produced in cardiovascular systems. Under physiological conditions, ROS/RNS function as …
produced in cardiovascular systems. Under physiological conditions, ROS/RNS function as …
AMPK in cardiovascular health and disease
NA Shirwany, MH Zou - Acta Pharmacologica Sinica, 2010 - nature.com
Abstract Adenosine Monophosphate-activated Protein Kinase (AMPK), a serine/threonine
kinase and a member of the Snf1/AMPK protein kinase family, consists of three protein …
kinase and a member of the Snf1/AMPK protein kinase family, consists of three protein …
AMPK and vasculoprotection
MA Ewart, S Kennedy - Pharmacology & therapeutics, 2011 - Elsevier
AMP-activated protein kinase (AMPK) is proposed to be a key regulator of cellular and
organismal metabolism and has reported vasculoprotective effects. In addition, many …
organismal metabolism and has reported vasculoprotective effects. In addition, many …
Inhibition of AMP kinase by the protein phosphatase 2A heterotrimer, PP2APpp2r2d
BK Joseph, HY Liu, J Francisco, D Pandya… - Journal of Biological …, 2015 - ASBMB
AMP kinase is a heterotrimeric serine/threonine protein kinase that regulates a number of
metabolic processes, including lipid biosynthesis and metabolism. AMP kinase activity is …
metabolic processes, including lipid biosynthesis and metabolism. AMP kinase activity is …
MicroRNA Let-7 targets AMPK and impairs hepatic lipid metabolism in offspring of maternal obese pregnancies
Nutritional status during gestation may lead to a phenomenon known as metabolic
programming, which can be triggered by epigenetic mechanisms. The Let-7 family of …
programming, which can be triggered by epigenetic mechanisms. The Let-7 family of …
[HTML][HTML] Dietary epicatechin promotes survival of obese diabetic mice and Drosophila melanogaster
The lifespan of diabetic patients is 7–8 y shorter than that of the general population because
of hyperglycemia-induced vascular complications and damage to other organs such as the …
of hyperglycemia-induced vascular complications and damage to other organs such as the …