Background Increasing digitalization enables the use of artificial intelligence (AI) and
machine learning in pathology. However, these technologies have only just begun to be …

Background The incidence of anal abscess and fistula is relatively high, and the condition is
most common in young men. Methods This is a revised version of the German S3 guidelines …

Colorectal cancer (CRC) is the third most common cancer worldwide. A diagnosis at early
stages with enhanced screening methods is vital as metastases and recurrences increase …

Background FIRE-3 compared first-line therapy with FOLFIRI plus either cetuximab or
bevacizumab in 592 KRAS exon 2 wild-type metastatic colorectal cancer (mCRC) patients …

In dieser Leitlinie sind eingetragene Warenzeichen (geschützte Warennamen) nicht
besonders kenntlich gemacht. Es kann also aus dem Fehlen eines entsprechenden …

Aberrant DNA methylation has shown promise as a biomarker for the early detection of
cancer. To discover novel genes frequently methylated at an early stage in colorectal cancer …

Globally, metastatic colorectal cancer is one of the leading causes for cancer-related death.
Treatment limited to conventional chemotherapeutics extended life for only a few months …

Endoscopic polypectomy and endoscopic mucosal resection (EMR) are the established
treatment standards for colorectal polyps. Current research aims at the reduction of both …

Background The main reason for treatment failure after curative surgical resection of gastric
cancer is intra-abdominal spread, with 40–50% peritoneal seeding as primary localization of …

Patients with hereditary gastrointestinal (GI) cancers represent a substantial fraction of the
overall affected population. Although awareness for hereditary GI cancer syndromes is on …