Articular cartilage has a low self-repair capacity due to the lack of vessels and nerves. In
recent times, nanofiber scaffolds have been widely used for this purpose. The optimum …

Humans and animals lose tissues and organs due to congenital defects, trauma, and
diseases. The human body has a low regenerative potential as opposed to the urodele …

Osteoarthritis (OA) is a chronic, prevalent, debilitating joint disease characterized by
progressive cartilage degradation, subchondral bone remodeling, bone marrow lesions …

Osteoarthritis (OA) is a degenerative disease characterized by loss of articular cartilage and
chronic inflammation, involving multiple cellular dysfunctions and tissue lesions. The non …

Articular hyaline cartilage is extensively hydrated, but it is neither innervated nor
vascularized, and its low cell density allows only extremely limited self-renewal. Most clinical …

There has been considerable advancement over the last few years in the treatment of
osteoarthritis, common chronic disease and a major cause of disability in older adults. In this …

Background: Matrix-based cell therapy improves surgical handling, increases patient
comfort, and allows for expanded indications with better reliability within the knee joint. Five …

Significant advances have been made in the field of tissue engineering (TE), especially in
the synthesis of three-dimensional (3D) scaffolds for replacing damaged tissues and organs …

Cell therapies offer a tailorable, personalized treatment for use in tissue engineering to
address defects arising from trauma, inefficient wound repair, or congenital malformation …

Osteoarthritis (OA) is a chronic joint disease characterized by progressive degeneration of
articular cartilage. A challenge in the development of disease-modifying drugs is effective …