[HTML][HTML] Targeting extracellular nutrient dependencies of cancer cells
J Garcia-Bermudez, RT Williams, R Guarecuco… - Molecular …, 2020 - Elsevier
Background Cancer cells rewire their metabolism to meet the energetic and biosynthetic
demands of their high proliferation rates and environment. Metabolic reprogramming of …
demands of their high proliferation rates and environment. Metabolic reprogramming of …
Acetate dependence of tumors
SA Comerford, Z Huang, X Du, Y Wang, L Cai… - Cell, 2014 - cell.com
Acetyl-CoA represents a central node of carbon metabolism that plays a key role in
bioenergetics, cell proliferation, and the regulation of gene expression. Highly glycolytic or …
bioenergetics, cell proliferation, and the regulation of gene expression. Highly glycolytic or …
[HTML][HTML] The clinical use of PET with 11C-acetate
I Grassi, C Nanni, V Allegri, JJ Morigi… - American journal of …, 2012 - ncbi.nlm.nih.gov
The aim of this review is to evaluate clinical applications of 11 C-acetate positron emission
tomography (PET). Acetate is quickly metabolized into acetyl-CoA in human cells. In this …
tomography (PET). Acetate is quickly metabolized into acetyl-CoA in human cells. In this …
SPECT and PET imaging of meningiomas
V Valotassiou, A Leondi, G Angelidis… - The Scientific World …, 2012 - Wiley Online Library
Meningiomas arise from the meningothelial cells of the arachnoid membranes. They are the
most common primary intracranial neoplasms and represent about 20% of all intracranial …
most common primary intracranial neoplasms and represent about 20% of all intracranial …
[HTML][HTML] Association of circulating short chain fatty acid levels with colorectal adenomas and colorectal cancer
F Genua, B Mirković, A Mullee, M Levy… - Clinical Nutrition …, 2021 - Elsevier
Background & aims Short chain fatty acid (SCFAs) are bacterially derived metabolites
suggested to have protective roles against colorectal cancer (CRC) development. However …
suggested to have protective roles against colorectal cancer (CRC) development. However …
[HTML][HTML] Regulation of acetate utilization by monocarboxylate transporter 1 (MCT1) in hepatocellular carcinoma (HCC)
Altered energy metabolism is a biochemical fingerprint of cancer cells. Hepatocellular
carcinoma (HCC) shows reciprocal [18 F] fluorodeoxyglucose (FDG) and [11 C] acetate …
carcinoma (HCC) shows reciprocal [18 F] fluorodeoxyglucose (FDG) and [11 C] acetate …
Loss of ACSS2 expression predicts poor prognosis in patients with gastric cancer
Background Recent studies have demonstrated that acetyl‐CoA synthetase 2 (ACSS2)
plays a critical role in cancer cell survival; however, the role of ACSS2 in gastric …
plays a critical role in cancer cell survival; however, the role of ACSS2 in gastric …
11C-acetate positron emission tomography is more precise than 18F-fluorodeoxyglucose positron emission tomography in evaluating tumor burden and predicting …
M Chen, W Zhu, J Du, C Yang, B Han, D Zhou… - Scientific Reports, 2021 - nature.com
The optimal method of tumor burden evaluation in newly diagnosed multiple myeloma
(NDMM) is yet to be determined. This study aimed to compare the value of 11C-acetate …
(NDMM) is yet to be determined. This study aimed to compare the value of 11C-acetate …
An integrated metabonomics study to reveal the inhibitory effect and metabolism regulation of taurine on breast cancer
W Chen, Q Li, R Hou, H Liang, Y Zhang… - Journal of Pharmaceutical …, 2022 - Elsevier
Breast cancer is a common metastatic malignant tumor in women. Taurine has been found
to have anti-tumor effects on a variety of cancers. However, to the best of our knowledge, the …
to have anti-tumor effects on a variety of cancers. However, to the best of our knowledge, the …
Correlation of quantified metabolic activity in nonsmall cell lung cancer with tumor size and tumor pathological characteristics
The aim of this study was to evaluate the relationship between maximum standardized
uptake value (SUV max) with tumor size and tumor pathological characteristics as well as …
uptake value (SUV max) with tumor size and tumor pathological characteristics as well as …