[HTML][HTML] Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases

L Recinella, G Orlando, C Ferrante… - Frontiers in …, 2020 - frontiersin.org
Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

[HTML][HTML] Anxiety, depression, and the microbiome: a role for gut peptides

G Lach, H Schellekens, TG Dinan, JF Cryan - Neurotherapeutics, 2018 - Elsevier
The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …

[HTML][HTML] The parabrachial nucleus: CGRP neurons function as a general alarm

RD Palmiter - Trends in neurosciences, 2018 - cell.com
The parabrachial nucleus (PBN), which is located in the pons and is dissected by one of the
major cerebellar output tracks, is known to relay sensory information (visceral malaise, taste …

[HTML][HTML] Current knowledge on endocrine disrupting chemicals (EDCs) from animal biology to humans, from pregnancy to adulthood: highlights from a national Italian …

ME Street, S Angelini, S Bernasconi, E Burgio… - International journal of …, 2018 - mdpi.com
Wildlife has often presented and suggested the effects of endocrine disrupting chemicals
(EDCs). Animal studies have given us an important opportunity to understand the …

Estrogen deficiency and the origin of obesity during menopause

F Lizcano, G Guzmán - BioMed research international, 2014 - Wiley Online Library
Sex hormones strongly influence body fat distribution and adipocyte differentiation.
Estrogens and testosterone differentially affect adipocyte physiology, but the importance of …

[HTML][HTML] Stress: endocrine physiology and pathophysiology

C Tsigos, I Kyrou, E Kassi, GP Chrousos - Endotext [Internet], 2020 - ncbi.nlm.nih.gov
Stress constitutes a state of threatened homeostasis triggered by intrinsic or extrinsic
adverse forces (stressors) and is counteracted by an intricate repertoire of physiologic and …

The effects of light at night on circadian clocks and metabolism

LK Fonken, RJ Nelson - Endocrine reviews, 2014 - academic.oup.com
Most organisms display endogenously produced∼ 24-hour fluctuations in physiology and
behavior, termed circadian rhythms. Circadian rhythms are driven by a transcriptional …

Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome

BL Wajchenberg - Endocrine reviews, 2000 - academic.oup.com
Methods for assessment, eg., anthropometric indicators and imaging techniques, of several
phenotypes of human obesity, with special reference to abdominal fat content, have been …

Biology's response to dieting: the impetus for weight regain

PS MacLean, A Bergouignan… - American Journal …, 2011 - journals.physiology.org
Dieting is the most common approach to losing weight for the majority of obese and
overweight individuals. Restricting intake leads to weight loss in the short term, but, by itself …