[HTML][HTML] Tobacco smoke induces and alters immune responses in the lung triggering inflammation, allergy, asthma and other lung diseases: a mechanistic review

A Strzelak, A Ratajczak, A Adamiec… - International journal of …, 2018 - mdpi.com
Many studies have been undertaken to reveal how tobacco smoke skews immune
responses contributing to the development of chronic obstructive pulmonary disease …

[HTML][HTML] Impacts of cigarette smoking on immune responsiveness: Up and down or upside down?

F Qiu, CL Liang, H Liu, YQ Zeng, S Hou, S Huang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Cigarette smoking is associated with numerous diseases and poses a serious challenge to
the current healthcare system worldwide. Smoking impacts both innate and adaptive …

[HTML][HTML] COPD immunopathology

G Caramori, P Casolari, A Barczyk, AL Durham… - Seminars in …, 2016 - Springer
The immunopathology of chronic obstructive pulmonary disease (COPD) is based on the
innate and adaptive inflammatory immune responses to the chronic inhalation of cigarette …

[HTML][HTML] The effect of smoking on chronic inflammation, immune function and blood cell composition

I Elisia, V Lam, B Cho, M Hay, MY Li, M Yeung, L Bu… - Scientific reports, 2020 - nature.com
Smoking is the number one risk factor for cancer mortality but only 15–20% of heavy
smokers develop lung cancer. It would, therefore, be of great benefit to identify those at high …

[HTML][HTML] Lung function and systemic inflammation associated with short-term air pollution exposure in chronic obstructive pulmonary disease patients in Beijing, China

N Gao, W Xu, J Ji, Y Yang, ST Wang, J Wang… - Environmental …, 2020 - Springer
Background Exposure to air pollution is associated with chronic obstructive pulmonary
disease (COPD). However, findings on the effects of air pollution on lung function and …

Airway inflammation in chronic obstructive pulmonary disease (COPD): a true paradox

MS Eapen, S Myers, EH Walters… - Expert review of …, 2017 - Taylor & Francis
Introduction: Chronic obstructive pulmonary disease (COPD) is primarily an airway
condition, which mainly affects cigarette smokers and presents with shortness of breath that …

[HTML][HTML] Th17/Treg imbalance in chronic obstructive pulmonary disease: clinical and experimental evidence

JD Lourenço, JT Ito, MA Martins, IFLC Tibério… - Frontiers in …, 2021 - frontiersin.org
The imbalance between pro-and anti-inflammatory immune responses mediated by Th17
and Treg cells is deeply involved in the development and progression of inflammation in …

[HTML][HTML] Respiratory viral infection: a potential “missing link” in the pathogenesis of COPD

D Linden, H Guo-Parke, PV Coyle… - European …, 2019 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is currently the third most common cause of
global mortality. Acute exacerbations of COPD frequently necessitate hospital admission to …

Xuanbai Chengqi decoction ameliorates pulmonary inflammation via reshaping gut microbiota and rectifying Th17/Treg imbalance in a murine model of chronic …

Y Wang, N Li, Q Li, Z Liu, Y Li, J Kong… - … journal of chronic …, 2021 - Taylor & Francis
Purpose Chronic obstructive pulmonary disease (COPD), a prevalent obstructive airway
disease, has become the third most common cause of death globally. Xuanbai Chengqi …

[HTML][HTML] Infection of Mycobacterium tuberculosis Promotes Both M1/M2 Polarization and MMP Production in Cigarette Smoke-Exposed Macrophages

Y Le, W Cao, L Zhou, X Fan, Q Liu, F Liu, X Gai… - Frontiers in …, 2020 - frontiersin.org
Pulmonary tuberculosis (PTB) is a risk factor for COPD. Our previous study revealed more
severe emphysema in COPD patients (mostly smokers) with prior tuberculosis. However, the …