Quercetin, epigallocatechin gallate, curcumin, and resveratrol: from dietary sources to human microRNA modulation

E Cione, C La Torre, R Cannataro, MC Caroleo… - Molecules, 2019 - mdpi.com
Epidemiologic studies suggest that dietary polyphenol intake is associated with a lower
incidence of several non-communicable diseases. Although several foods contain complex …

The implication of reactive oxygen species and antioxidants in knee osteoarthritis

NB Tudorachi, EE Totu, A Fifere, V Ardeleanu… - Antioxidants, 2021 - mdpi.com
Knee osteoarthritis (KOA) is a chronic multifactorial pathology and a current and essential
challenge for public health, with a negative impact on the geriatric patient's quality of life …

Curcumin reinforces MSC‐derived exosomes in attenuating osteoarthritis via modulating the miR‐124/NF‐kB and miR‐143/ROCK1/TLR9 signalling pathways

B Qiu, X Xu, P Yi, Y Hao - Journal of Cellular and Molecular …, 2020 - Wiley Online Library
Curcumin treatment was reported to delay the progression of OA, but its underlying
mechanism remains unclear. In this study, we aimed to investigate the molecular …

Anti-inflammatory effects of dietary polyphenols through inhibitory activity against metalloproteinases

T Suzuki, T Ohishi, H Tanabe, N Miyoshi, Y Nakamura - Molecules, 2023 - mdpi.com
Matrix metalloproteinases (MMPs) are zinc-dependent metalloproteinases that play
important roles in a variety of diseases, including cancer, cardiovascular disease, diabetes …

Curcumin in autoimmune and rheumatic diseases

M Yang, U Akbar, C Mohan - Nutrients, 2019 - mdpi.com
Over recent decades, many clinical trials on curcumin supplementation have been
conducted on various autoimmune diseases including osteoarthritis, type 2 diabetes, and …

A Next Generation Formulation of Curcumin Ameliorates Experimentally Induced Osteoarthritis in Rats via Regulation of Inflammatory Mediators

M Yabas, C Orhan, B Er, M Tuzcu, AS Durmus… - Frontiers in …, 2021 - frontiersin.org
Osteoarthritis (OA) is a chronic and debilitating disease of the knee joint. OA of the knee is
initiated by physical damage and accumulated oxidative stress, followed by an exaggerated …

[HTML][HTML] A carrier-free nano-drug assembled via π–π stacking interaction for the treatment of osteoarthritis

W Dai, P Jin, X Li, J Zhao, Y Lan, H Li… - Biomedicine & …, 2023 - Elsevier
Osteoarthritis (OA) is considered to be the most common joint disorder. Exogenous drug
intervention is one of the effective means for OA treatment. Clinical applications of numerous …

Exosomes isolated from bone marrow mesenchymal stem cells exert a protective effect on osteoarthritis via lncRNA LYRM4-AS1-GRPR-miR-6515-5p

X Wang, Z Li, Y Cui, X Cui, C Chen… - Frontiers in cell and …, 2021 - frontiersin.org
Objectives The aim of this study was to investigate the effects of exosomes isolated from
human bone marrow mesenchymal stem cells (BMSCs) on osteoarthritis (OA) and a …

In Vitro Study of the Anti-inflammatory and Antifibrotic Activity of Tannic Acid-Coated Curcumin-Loaded Nanoparticles in Human Tenocytes

G Molinaro, F Fontana, R Pareja Tello… - … Applied Materials & …, 2023 - ACS Publications
Tendinitis is a tendon disorder related to inflammation and pain, due to an injury or overuse
of the tissue, which is hypocellular and hypovascular, leading to limited repair which occurs …

Potential complementary and/or synergistic effects of curcumin and boswellic acids for management of osteoarthritis

V Sethi, M Garg, M Herve… - Therapeutic Advances in …, 2022 - journals.sagepub.com
For several thousand years (~ 4000) Boswellia serrata and Curcuma longa have been used
in Aryuvedic medicine for treatment of various illnesses, including asthma, peptic ulcers, and …