Aims The associations of 2 nonsynonymous single nucleotide polymorphisms (Arg16Gly
and Gln27Glu) in the adrenoceptor β2 (ADRB2) gene with response after albuterol use are …

For the past half-century, β 2-agonists have been the mainstay of treatment of the
bronchoconstriction associated with asthma. Although their usefulness in reversing acute …

Background. About 9% of children have asthma, corresponding to almost 6.8 million
children in the USA and 1.1 million in the UK. Asthma exacerbations are the leading cause …

Background Rates of asthma in Jordan have been doubled in the past decade, but this
increased prevalence was not met with improved asthma control protocols. The aim of the …

The β 2-adrenergic receptor (β 2 AR) is a membrane-bound G-protein-coupled receptor and
an important drug target for asthma. Clinical studies report that the population variant …

Background: The ß2-adrenergic receptors are cell surface receptors playing a central role in
the pharmacological targeting asthma and chronic obstructive pulmonary disease (COPD) …

BACKGROUND: Inhaled β2-adrenergic receptor (β2-AR) agonists are the mainstay of
treatment of acute asthma. Polymorphisms of the β2-AR, especially codons 16, 27, and 164 …

Introduction The bronchodilator response (BDR) depends on many factors, including genetic
ones. Numerous single nucleotide polymorphisms (SNPs) influencing BDR have been …

Background Albuterol is one of the most frequently used medications in clinical practice and
seeing varying responses to albuterol between individuals is not uncommon. Multiple …

Asthma is a respiratory condition often stemming from childhood, characterized by difficulty
breathing and/or chest tightness. Current treatment options for both adults and children …