IL-12 and IL-23 pathway inhibition in inflammatory bowel disease

B Verstockt, A Salas, BE Sands, C Abraham… - Nature Reviews …, 2023 - nature.com
Abstract Interleukin-12 (IL-12) and interleukin-23 (IL-23), which belong to the IL-12 family of
cytokines, have a key role in intestinal homeostasis and inflammation and are implicated in …

[HTML][HTML] The relapse of psoriasis: mechanisms and mysteries

D Tian, Y Lai - JID Innovations, 2022 - Elsevier
Over the past decades, tremendous success in the treatment of psoriasis has been achieved
using biologics, such as neutralizing antibodies against TNF/TNFR, IL-23, and IL-17A/IL …

Signaling pathways and targeted therapies for psoriasis

J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Paradoxical eruptions to targeted therapies in dermatology: a systematic review and analysis

MJ Murphy, JM Cohen, MD Vesely… - Journal of the American …, 2022 - Elsevier
Background Antibody-based therapies that inhibit proinflammatory cytokine signaling are
commonly used in dermatology. Paradoxically, these medications may induce or exacerbate …

Comorbidity in adult psoriasis: considerations for the clinician

C Daugaard, L Iversen, KF Hjuler - Psoriasis: Targets and Therapy, 2022 - Taylor & Francis
Psoriasis is associated with several comorbidities ranging from cardiovascular comorbidity
and mental disorders to other immune mediated inflammatory diseases. However, most of …

Adipose‐derived biogenic nanoparticles for suppression of inflammation

M Tian, T Ticer, Q Wang, S Walker, A Pham, A Suh… - Small, 2020 - Wiley Online Library
Extracellular vesicles secreted from adipose‐derived mesenchymal stem cells (ADSCs)
have therapeutic effects in inflammatory diseases. However, production of extracellular …

[HTML][HTML] Preparation and characterization of solid lipid nanoparticles encapsulated noscapine and evaluation of its protective effects against imiquimod-induced …

P Rahmanian-Devin, VR Askari, Z Sanei-Far… - Biomedicine & …, 2023 - Elsevier
Psoriasis is a chronic inflammatory skin disease characterized by thickening the epidermis
with erythema, scaling, and proliferation. Noscapine (NOS) has several anti-inflammatory …

The impact of diet and physical activity on psoriasis: a narrative review of the current evidence

E Duchnik, J Kruk, A Tuchowska, M Marchlewicz - Nutrients, 2023 - mdpi.com
Psoriasis is an inflammatory disease with strong genetic links and numerous features of
autoimmunity that are also influenced by environment and lifestyle, including nutritional …

Reversing the Inflammatory Process—25 Years of Tumor Necrosis Factor-α Inhibitors

KN Muth, J Rech, FO Losch, A Hoerning - Journal of Clinical Medicine, 2023 - mdpi.com
Immune-mediated inflammatory diseases, such as rheumatoid arthritis, psoriatic arthritis,
peripheral and/or axial spondyloarthritis, Crohn's disease, and ulcerative colitis, are …

Immune effects of macrophages in rheumatoid arthritis: a bibliometric analysis from 2000 to 2021

YL Xu, Z Zhang, J He, Z Chen - Frontiers in Immunology, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease characterized by
macrophage activation. The current characteristics, hotspots, and research frontiers of …