There is growing recognition that tuberculosis (TB) infection and disease exists as a
spectrum of states beyond the current binary classification of latent and active TB. Our aim …

Although the importance of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA)
sensors in controlling viral infection is well established, their role in promoting an effective …

Abstract Mycobacterium tuberculosis (Mtb) reprograms FAs metabolism of macrophages
during infection and affects inflammatory reaction eventually, however, the mechanism …

Toxin–Antitoxin (TA) systems are some small genetic modules in bacteria that play
significant roles in resistance and tolerance development to antibiotics. Whole genome …

Epigenetics is a term that refers to all those modifications to gene expression due to the
interaction of genes with the environment. These modifications do not imply any changes in …

Background: Latent Tuberculosis Infection (LTBI) is a state of persistent immune response to
stimulation by Mycobacterium tuberculosis antigens with no clinical evidence of active TB …

Drug reaction with eosinophilia and systemic syndrome (DRESS) is a life-threatening
hypersensitivity reaction of the skin and visceral organs caused by exposure to certain …

Background Tuberculosis (TB) is a global health threat. The World Health Organization
mandates surveillance of drug-resistant TB (DR-TB) in high-burden countries. This study …