The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …

Advances in anion transport by synthetic supramolecular systems are discussed in this
article. Developments in the design of discrete molecular carriers for anions and …

Salt and fluid absorption and secretion are two processes that are fundamental to epithelial
function and whole body fluid homeostasis, and as such are tightly regulated in epithelial …

Mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator
undermine many host defense systems by inhibiting the function of airway-surface liquid …

In cystic fibrosis (CF) airways, Pseudomonas aeruginosa forms cellular aggregates called
biofilms that are thought to contribute to chronic infection. To form aggregates, P. aeruginosa …

Lung disease is the major cause of morbidity and mortality in patients with cystic fibrosis
(CF). Although CF lung disease is primarily an infectious disorder, the associated …

Cystic fibrosis (CF) is a life-shortening disease caused by mutations in the cystic fibrosis
transmembrane conductance regulator (CFTR) gene. Although bacterial lung infection and …

Nanosized crosslinked polymer networks, named as nanogels, are playing an increasingly
important role in a diverse range of applications by virtue of their porous structures, large …

Cystic fibrosis transmembrane conductance regulator (CFTR) functions as a channel that
regulates the transport of ions and the movement of water across the epithelial barrier …

Cystic fibrosis (CF) disrupts respiratory host defenses, allowing bacterial infection,
inflammation, and mucus accumulation to progressively destroy the lungs. Our previous …