Autoantibodies to glutamic acid decarboxylase in patients with IDDM and autoimmune thyroid disease

E Kawasaki, H Takino, M Yano, S Uotani… - Diabetes, 1994 - Am Diabetes Assoc
Autoantibodies to glutamic acid decarboxylase (GAD), previously reported to be the 64,000-
M r (64K) islet cell protein, were measured by a radioimmunoassay using purified pig brain …

Antibodies to glutamic acid decarboxylase discriminate major types of diabetes mellitus

MJ Rowley, IR Mackay, QY Chen, WJ Knowles… - Diabetes, 1992 - Am Diabetes Assoc
Insulin-dependent diabetes mellitus (IDDM) is marked by circulating antibodies to a 64,000-
Mr islet cell antigen identified as glutamic acid decarboxylase (GAD). We describe a …

Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset …

J Endl, H Otto, G Jung, B Dreisbusch… - The Journal of …, 1997 - Am Soc Clin Investig
Glutamic acid decarboxylase (GAD) has been defined as a major target antigen in insulin-
dependent diabetes mellitus (IDDM). To identify the molecular ligands triggering a T cell …

Glutamate decarboxylase

JY Wu, LA Denner, CT Lin… - Glutamine and Glutamate …, 2018 - taylorfrancis.com
l-Glutamate decarboxylase (GAD) which catalyzes the conversion of l-glutamate to γ-
aminobutyric acid, an important inhibitory neurotransmitter, is a specific marker for γ …

Cloning of the gene for glutamate decarboxylase and its expression during conidiation in Neurospora crassa

R Hao, JC Schmit - Biochemical Journal, 1993 - portlandpress.com
Neurospora crassa glutamate decarboxylase (GAD) is produced during conidiation and
stored in dormant conidia. Polyclonal antibody was generated to GAD that had been purified …

Autoantibodies to glutamic acid decarboxylase in patients with autoimmune thyroid disease: relation to competitive insulin autoantibodies

E Kawasaki, N Abiru, M Yano, S Uotani… - Journal of …, 1995 - Elsevier
We evaluated the presence of autoantibodies to glutamic acid decarboxylase (GAD),
competitive insulin autoantibodies (IAA) and islet cell antibodies (ICA) in sera from 288 non …

Proton/l-Glutamate Symport and the Regulation of Intracellular pH in Isolated Mesophyll Cells

WA Snedden, I Chung, RH Pauls, AW Bown - Plant Physiology, 1992 - academic.oup.com
Abstract Addition of l-[U-14C] glutamate to a suspension of mechanically isolated asparagus
(Asparagus sprengeri Regel) mesophyll cells results in (a) alkalinization of the medium,(b) …

[HTML][HTML] Purification and characterization of glutamate decarboxylase from Neurospora crassa conidia.

R Hao, JC Schmit - Journal of Biological Chemistry, 1991 - Elsevier
L-Glutamate decarboxylase, an enzyme under the control of the asexual developmental
cycle of Neurospora crassa, was purified to homogeneity from conidia. The purification …

Plasma concentrations of glutamate and its metabolites in patients with Alzheimer's disease

FN Schwartz, DE Miulli, DY Norwell - Journal of Osteopathic …, 1993 - degruyter.com
Neurologic and psychologic tests without brain tissue biopsy do not establish the diagnosis
of Alzheimer's disease. This pilot study demonstrates significant increases in the activity of …

Interaction between Pyridoxal Kinase and Pyridoxal-5-phosphate–Dependent Enzymes

PY Cheung, CC Fong, KT Ng, WC Lam… - Journal of …, 2003 - academic.oup.com
The interactions of two pyridoxal-5-phosphate (PLP)–dependent enzymes, alanine
aminotransferase (ALT) and glutamate decarboxylase (GAD), with pyridoxal kinase (PK) …