The tail of the striatum: from anatomy to connectivity and function

E Valjent, G Gangarossa - Trends in neurosciences, 2021 - cell.com
The dorsal striatum, the largest subcortical structure of the basal ganglia, is critical in
controlling motor, procedural, and reinforcement-based behaviors. Although in mammals the …

[HTML][HTML] Integrating the roles of midbrain dopamine circuits in behavior and neuropsychiatric disease

APF Chen, L Chen, TA Kim, Q Xiong - Biomedicines, 2021 - mdpi.com
Dopamine (DA) is a behaviorally and clinically diverse neuromodulator that controls CNS
function. DA plays major roles in many behaviors including locomotion, learning, habit …

Distinct roles for motor cortical and thalamic inputs to striatum during motor skill learning and execution

SBE Wolff, R Ko, BP Ölveczky - Science advances, 2022 - science.org
The acquisition and execution of motor skills are mediated by a distributed motor network,
spanning cortical and subcortical brain areas. The sensorimotor striatum is an important cog …

Keeping time and rhythm by internal simulation of sensory stimuli and behavioral actions

V de Lafuente, M Jazayeri, H Merchant… - Science …, 2024 - science.org
Effective behavior often requires synchronizing our actions with changes in the environment.
Rhythmic changes in the environment are easy to predict, and we can readily time our …

[HTML][HTML] Cilia in the striatum mediate timing-dependent functions

W Alhassen, S Alhassen, J Chen, RV Monfared… - Molecular …, 2023 - Springer
Almost all brain cells contain cilia, antennae-like microtubule-based organelles. Yet, the
significance of cilia, once considered vestigial organelles, in the higher-order brain functions …

A neurodevelopmental signature of parkinsonism in schizophrenia

RC Wolf, KM Kubera, JL Waddington… - Schizophrenia …, 2021 - Elsevier
While sensorimotor abnormalities in schizophrenia (SZ) are of increasing scientific interest,
little is known about structural changes and their developmental origins that may underlie …

The central medial thalamic nucleus facilitates bilateral movement execution in rats

AY Luma, CI Perez, AK Pimentel-Farfan… - Neuroscience, 2022 - Elsevier
Intralaminar thalamic nuclei, including the central medial nucleus (CMT), have been
classically implicated in the control of attentional functional states such as sleep-wake …

Contributions of Basal Ganglia Circuits to Perception, Attention, and Consciousness

MJ Redinbaugh, YB Saalmann - Journal of Cognitive Neuroscience, 2024 - direct.mit.edu
Research into ascending sensory pathways and cortical networks has generated detailed
models of perception. These same cortical regions are strongly connected to subcortical …

[HTML][HTML] Striatal neurons partially expressing a dopaminergic phenotype: functional significance and regulation

D Troshev, A Bannikova, V Blokhin… - International Journal of …, 2022 - mdpi.com
Since the discovery of striatal neurons expressing dopamine-synthesizing enzymes,
researchers have attempted to identify their phenotype and functional significance. In this …

[HTML][HTML] NADPH and mito-apocynin treatment protects against KA-induced excitotoxic injury through autophagy pathway

N Liu, MM Lin, SS Huang, ZQ Liu, JC Wu… - Frontiers in Cell and …, 2021 - frontiersin.org
Aim Previous research recognizes that NADPH can produce reduced glutathione (GSH) as
a coenzyme and produce ROS as a substrate of NADPH oxidase (NOX). Besides, excessive …