This review presents several aspects of the innovative concept of sebaceous
immunobiology, which summarizes the numerous activities of the sebaceous gland …

Hair follicles, which are connected to sebaceous glands in the skin, undergo cyclic periods
of regeneration, degeneration, and rest throughout adult life in mammals. The crucial …

Hair follicle stem cells are regulated by dermal papilla fibroblasts, their principal signaling
niche. Overactivation of Hedgehog signaling in the niche dramatically accelerates hair …

Hair follicle stem cells (HFSCs) reside in the bulge region of the outer root sheath of the hair
follicle. They are considered slow-cycling cells that are endowed with multilineage …

Stem cells are the essential source of building blocks for tissue homeostasis and
regeneration. Their behavior is dictated by both cell‐intrinsic cues and extrinsic cues from …

Regeneration is a complex process affected by many elements independent or combined,
including inflammation, proliferation, and tissue remodeling. Stem cells is a class of primitive …

Alopecia areata (AA) is a type of dermatological disease characterized by rapid and non-
scarring hair loss of the scalp or body skin that may be related to genetic, immunological and …

The circadian clock adapts to the light–dark cycle and autonomously generates
physiological and metabolic rhythmicity. Its activity depends on the central suprachiasmatic …

Hair loss, or alopecia, is a dermatological disorder that causes psychological stress and
poor quality of life. Drug-based therapeutics such as finasteride and minoxidil have been …

Multipotent bulge stem cells (SCs) fuel the hair follicle (HF) cyclic growth during adult skin
homeostasis, but their intrinsic molecular heterogeneity is not well understood. These hair …