Studying bacterial infections through culture-independent approaches

GB Rogers, MP Carroll… - Journal of medical …, 2009 - microbiologyresearch.org
The ability to characterize accurately the cause of infection is fundamental to effective
treatment. The impact of any antimicrobial agents used to treat infection will, however …

Partitioning core and satellite taxa from within cystic fibrosis lung bacterial communities

CJ Van Der Gast, AW Walker, FA Stressmann… - The ISME …, 2011 - academic.oup.com
Cystic fibrosis (CF) patients suffer from chronic bacterial lung infections that lead to death in
the majority of cases. The need to maintain lung function in these patients means that …

Next-generation sequencing in the analysis of human microbiota: essential considerations for clinical application

GB Rogers, KD Bruce - Molecular diagnosis & therapy, 2010 - Springer
The development of next-generation sequencing (NGS) presents an unprecedented
opportunity to investigate the complex microbial communities that are associated with the …

Short-term comparative study of high frequency chest wall oscillation and European airway clearance techniques in patients with cystic fibrosis

LP Osman, M Roughton, ME Hodson, JA Pryor - Thorax, 2010 - thorax.bmj.com
Background High frequency chest wall oscillation (HFCWO) is standard treatment for airway
clearance in the USA and has recently been introduced in the UK and Europe. There is little …

High-throughput surface liquid absorption and secretion assays to identify F508del CFTR correctors using patient primary airway epithelial cultures

A Berg, S Hallowell, M Tibbetts… - … Life Sciences R&D, 2019 - journals.sagepub.com
High-throughput screening for drug discovery is increasingly utilizing cellular systems of
high physiological relevance, such as patient primary cells and organoid cultures. We used …

Cystic Fibrosis in the 21st Century.

NJ Simmonds - Current Medical Literature: Respiratory …, 2010 - search.ebscohost.com
The article provides information on cystic fibrosis (CF) including survival trends, disease
variability and future treatment choices. CF refers to a genetic disorder that has a …

Место гипертонического раствора хлорида натрия в терапии муковисцидоза

НЮ Каширская, ВД Шерман, НИ Капранов… - …, 2016 - journal.pulmonology.ru
Аннотация Прогноз заболевания при муковисцидозе (МВ) в подавляющем
большинстве случаев определяется выраженностью поражения бронхо-легочной …

A role of hypertonic saline solution in treatment of cystic fibrosis

NY Kashirskaya, VD Sherman… - …, 2016 - journal.pulmonology.ru
Outcomes and prognosis in cystic fibrosis (CF) are generally related to severity of respiratory
system injury. That is why new therapeutic methods are in focus. Mucolytic agents play an …

PSEUDO-BARTTER'S SYNDROME IN PATIENTS WITH CYSTIC FIBROSIS.

E TUTAR, P BORAN, S ÖKTEM… - Journal of Pediatric …, 2012 - search.ebscohost.com
ABSTRACT Background: Pseudo-Bartter's syndrome (PBS) is a clinical entity characterized
by hypokalemia, hypochloremia associated with metabolic alkalosis. It is different from …

Kistik fibrozisli Hastalarda Psödo-bartter Sendromu

E TUTAR, P BORAN, S ÖKTEM, Ö AKINCI… - Türkiye Çocuk …, 2012 - dergipark.org.tr
Giriş ve Amaç: Psödo-Bartter sendromu (PBS), hipokalemik, hipokloremik metabolik alkaloz
ile karakterize klinik bir tablodur. Bartter sendromundan farklı olarak, elektrolit kaybı böbrek …