Severe cardiotoxic effects limit the efficacy of doxorubicin (DOX) as a chemotherapeutic
agent. Activation of intracellular stress signaling networks, including p38 mitogen-activated …

Doxorubicin (DOX) is a broad-spectrum and highly efficient anticancer agent, but its clinical
implication is limited by lethal cardiotoxicity. Growing evidences have shown that alterations …

Despite their relative abundance, the role of B lympho-cytes (B-cells) in healthy murine
myocardial tissue has not been elucidated. Constituting≈ 20% of myocardial immune …

The importance of self-care to improve health and social well-being is well recognised.
Nevertheless, there remains a need to encourage people to better understand how their …

This study aimed to investigate the effect of constant heat flux on the adsorption of
doxorubicin by bio-MOF-11 biocarrier using molecular dynamics simulation. The research …

Purpose Doxorubicin-induced cardiotoxicity (DIC) is a severe side reaction in cancer
chemotherapy that greatly impacts the well-being of cancer patients. Currently, there is still …

Background and aims The cardiotoxicity related to 5-Fluorouracil (5-FU) in cancer patients
has garnered widespread attention. The systemic immune-inflammation index (SII) has …

Based on a few studies, heart failure patients with breast cancer were assessed to find
potential biomarkers for doxorubicin-induced cardiotoxicity. However, key immune-related …

The complete molecular mechanism underlying doxorubicin-induced cardiomyopathy
remains incompletely elucidated. In this investigation, we engineered mice with …

Background Doxorubicin (DOX) is a highly effective and widely used cytotoxic agent with
application for various malignancies, but it's clinically limited due to its cardiotoxicity …