[HTML][HTML] Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases

L Recinella, G Orlando, C Ferrante… - Frontiers in …, 2020 - frontiersin.org
Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

Chemerin: a multifaceted adipokine involved in metabolic disorders

G Helfer, QF Wu - Journal of Endocrinology, 2018 - joe.bioscientifica.com
Metabolic syndrome is a global public health problem and predisposes individuals to
obesity, diabetes and cardiovascular disease. Although the underlying mechanisms remain …

[HTML][HTML] Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training

CK Roberts, AL Hevener, RJ Barnard - Comprehensive physiology, 2013 - ncbi.nlm.nih.gov
Metabolic syndrome (MS) is a collection of cardiometabolic risk factors that includes obesity,
insulin resistance, hypertension, and dyslipidemia. Although there has been significant …

[PDF][PDF] Neutrophils, from marrow to microbes

N Borregaard - Immunity, 2010 - cell.com
Neutrophils are produced in the bone marrow from stem cells that proliferate and
differentiate to mature neutrophils fully equipped with an armory of granules. These contain …

The importance of breast adipose tissue in breast cancer

C Kothari, C Diorio, F Durocher - International journal of molecular …, 2020 - mdpi.com
Adipose tissue is a complex endocrine organ, with a role in obesity and cancer. Adipose
tissue is generally linked to excessive body fat, and it is well known that the female breast is …

[PDF][PDF] Role of adipokines in cardiovascular

HS Mattu, HS Randeva - J Endocrinol, 2013 - scholar.archive.org
The discovery of leptin in 1994 sparked dramatic new interest in the study of white adipose
tissue. It is now recognised to be a metabolically active endocrine organ, producing …

Involvement of novel adipokines, chemerin, visfatin, resistin and apelin in reproductive functions in normal and pathological conditions in humans and animal models

A Estienne, A Bongrani, M Reverchon, C Ramé… - International journal of …, 2019 - mdpi.com
It is well known that adipokines are endocrine factors that are mainly secreted by white
adipose tissue. Their central role in energy metabolism is currently accepted. More recently …

Chemerin: at the crossroads of inflammation and obesity

MC Ernst, CJ Sinal - Trends in Endocrinology & Metabolism, 2010 - cell.com
Chemerin is a secreted protein with a complex but well-established role in immune function.
Parallel lines of investigation also support the notion that chemerin is a novel adipokine that …

Towards an integrative approach to understanding the role of chemerin in human health and disease

JL Rourke, HJ Dranse, CJ Sinal - Obesity Reviews, 2013 - Wiley Online Library
Chemerin is an adipocyte‐secreted protein with autocrine/paracrine roles on adipose
development and function as well as endocrine roles in metabolism and immunity. Following …

Chemerin isoforms and activity in obesity

C Buechler, S Feder, EM Haberl… - International journal of …, 2019 - mdpi.com
Overweight and adiposity are risk factors for several diseases, like type 2 diabetes and
cancer. White adipose tissue is a major source for adipokines, comprising a diverse group of …