Implications of nonshivering thermogenesis for energy balance regulation in humans

WD van Marken Lichtenbelt… - American Journal of …, 2011 - journals.physiology.org
The incidence of the metabolic syndrome has reached epidemic levels in the Western world.
With respect to the energy balance, most attention has been given to reducing energy (food) …

Brown adipose tissue in adult humans: a metabolic renaissance

P Lee, MM Swarbrick, KKY Ho - Endocrine reviews, 2013 - academic.oup.com
Brown adipose tissue (BAT) plays a key role in energy homeostasis and thermogenesis in
animals, conferring protection against diet-induced obesity and hypothermia through the …

Impact of age on the relationships of brown adipose tissue with sex and adiposity in humans

C Pfannenberg, MK Werner, S Ripkens, I Stef… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Brown adipose tissue (BAT) regulates energy homeostasis and fat mass in
mammals and newborns and, most likely, in adult humans. Because BAT activity and BAT …

[PDF][PDF] White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis

L Cao, EY Choi, X Liu, A Martin, C Wang, X Xu… - Cell metabolism, 2011 - cell.com
Living in an enriched environment with complex physical and social stimulation leads to
improved cognitive and metabolic health. In white fat, enrichment induced the upregulation …

[PDF][PDF] Myosin ATP Turnover Rate: a Mechanism Involved in Thermogenesis in Resting Skeletal Muscle Fibers

MA Stewart - Biophysical Journal, 2010 - cell.com
Thermogenesis by resting muscle varies with conditions and plays an active role in
homeostasis of body weight. The low metabolic rate of living resting muscles requires that …

Dynamic changes in lipid droplet-associated proteins in the “browning” of white adipose tissues

D Barneda, A Frontini, S Cinti, M Christian - Biochimica Et Biophysica Acta …, 2013 - Elsevier
The morphological and functional differences between lipid droplets (LDs) in brown (BAT)
and white (WAT) adipose tissues will largely be determined by their associated proteins …

BAT: a new target for human obesity?

G Frühbeck, S Becerril, N Sáinz, P Garrastachu… - Trends in …, 2009 - cell.com
Two types of adipose tissue can be distinguished histologically and functionally: white
(WAT) and brown adipose tissue (BAT). Whereas BAT is specialized in the production of …

Systemic β-adrenergic stimulation of thermogenesis is not accompanied by brown adipose tissue activity in humans

MJ Vosselman, AAJJ Van der Lans, B Brans… - Diabetes, 2012 - Am Diabetes Assoc
Brown adipose tissue (BAT) is currently considered as a target to combat obesity and
diabetes in humans. BAT is densely innervated by the sympathetic nervous system (SNS) …

[HTML][HTML] Effects of polyphenols on thermogenesis and mitochondrial biogenesis

T Wood dos Santos, Q Cristina Pereira… - International journal of …, 2018 - mdpi.com
Obesity is a health problem worldwide, and energy imbalance has been pointed out as one
of the main factors responsible for its development. As mitochondria are a key element in …

[HTML][HTML] Brown fat in humans: turning up the heat on obesity

P Seale, MA Lazar - Diabetes, 2009 - ncbi.nlm.nih.gov
The looming pandemic of obesity and overweight, driven by ready access to high-calorie
food and an increasingly sedentary way of life, poses a severe threat to global public health …