Endogenous UVA-photosensitizers: mediators of skin photodamage and novel targets for skin photoprotection

GT Wondrak, MK Jacobson… - … & photobiological sciences, 2006 - pubs.rsc.org
Endogenous chromophores in human skin serve as photosensitizers involved in skin
photocarcinogenesis and photoaging. Absorption of solar photons, particularly in the UVA …

Malignant melanoma: an update

A Slominski, J Wortsman, AJ Carlson… - … of pathology & …, 2001 - meridian.allenpress.com
Context.—The rapidly developing fields of melanoma research are revolutionizing the
current concepts on melanoma etiology and pathogenesis and are introducing newer …

Characterization of CD4+CD25+ Regulatory T Cells in Patients Treated With High-Dose Interleukin-2 for Metastatic Melanoma or Renal Cell Carcinoma

GC Cesana, G DeRaffele, S Cohen… - Journal of Clinical …, 2006 - ascopubs.org
Purpose To characterize the number and functional status of CD4+ CD25+ regulatory T cells
(Tregs) in patients with metastatic melanoma (MM) and renal cell carcinoma (RCC) treated …

S100B protein detection in serum is a significant prognostic factor in metastatic melanoma

A Hauschild, G Engel, W Brenner, R Gläser, H Mönig… - Oncology, 1999 - karger.com
The serum detection of S100B, a new melanoma marker, has shown clinical significance in
early studies. The aim of our study of 1,339 serum samples from 412 different melanoma …

Gadolinium doping enhances the photoacoustic signal of synthetic melanin nanoparticles: a dual modality contrast agent for stem cell imaging

JE Lemaster, Z Wang, A Hariri, F Chen, Z Hu… - Chemistry of …, 2018 - ACS Publications
In this paper, we show that gadolinium-loaded synthetic melanin nanoparticles (Gd (III)-
SMNPs) exhibit up to a 40-fold enhanced photoacoustic signal intensity relative to synthetic …

Serological markers for melanoma

L Brochez, JM Naeyaert - British Journal of Dermatology, 2000 - academic.oup.com
We present a review of current literature concerning the significance of serological markers
in melanoma patients. Results for cytokines, cytokine receptors, cell adhesion molecules …

Determination of the l-DOPA/l-tyrosine ratio in human plasma by high-performance liquid chromatography: Usefulness as a marker in metastatic malignant melanoma

S Letellier, JP Garnier, J Spy, B Bousquet - Journal of Chromatography B …, 1997 - Elsevier
A first procedure was devised for determining 3, 4-dihydroxyphenylalanine (l-DOPA) in
human plasma by isocratic RP-HPLC coupled with electrochemical detection. A second …

A frame-shift mutation in COMTD1 is associated with impaired pheomelanin pigmentation in chicken

H Bi, J Tranell, DC Harper, W Lin, J Li… - PLoS …, 2023 - journals.plos.org
The biochemical pathway regulating the synthesis of yellow/red pheomelanin is less well
characterized than the synthesis of black/brown eumelanin. Inhibitor of gold (IG phenotype) …

Chemistry of melanins

S Ito, K Wakamatsu - The pigmentary system: physiology and …, 2006 - Wiley Online Library
Summary 1 Melanin pigments can be classified into two major groups: the brown to black
insoluble eumelanins and the alkali-soluble yellow to reddish-brown pheomelanins. Both …

Evaluation of 5-S-cysteinyldopa as a marker of melanoma progression: 10 years' experience

K Wakamatsu, T Kageshita, M Furue, N Hatta… - Melanoma …, 2002 - journals.lww.com
S-Cysteinyldopa (5-S-CD) has been used as a biochemical marker of melanoma
progression. In this study, we measured serum levels of 5-S-CD in 2648 samples taken from …