Omega-3 fatty acids and cancer cell cytotoxicity: implications for multi-targeted cancer therapy

D D'Eliseo, F Velotti - Journal of clinical medicine, 2016 - mdpi.com
Cancer is a major disease worldwide. Despite progress in cancer therapy, conventional
cytotoxic therapies lead to unsatisfactory long-term survival, mainly related to development …

Health benefits of docosahexaenoic acid (DHA)

LA Horrocks, YK Yeo - Pharmacological research, 1999 - Elsevier
Docosahexaenoic acid (DHA) is essential for the growth and functional development of the
brain in infants. DHA is also required for maintenance of normal brain function in adults. The …

The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina

JP SanGiovanni, EY Chew - Progress in retinal and eye research, 2005 - Elsevier
In this work we advance the hypothesis that omega-3 (ω-3) long-chain polyunsaturated fatty
acids (LCPUFAs) exhibit cytoprotective and cytotherapeutic actions contributing to a number …

Nutraceuticals and functional foods: whole versus processed foods

F Shahidi - Trends in Food Science & Technology, 2009 - Elsevier
The importance of functional foods, nutraceuticals and other natural health products has
been well recognized in connection with health promotion, disease risk reduction and …

Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)

BN Hannafon, KJ Carpenter, WL Berry, R Janknecht… - Molecular cancer, 2015 - Springer
Background Docosahexaenoic acid (DHA) is a natural compound with anticancer and anti-
angiogenesis activity that is currently under investigation as both a preventative agent and …

Multi-targeted therapy of cancer by omega-3 fatty acids

IM Berquin, IJ Edwards, YQ Chen - Cancer letters, 2008 - Elsevier
Omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acids (PUFAs) are essential fatty
acids necessary for human health. Currently, the Western diet contains a disproportionally …

Are all n-3 polyunsaturated fatty acids created equal?

BM Anderson, DWL Ma - Lipids in health and Disease, 2009 - Springer
N-3 Polyunsaturated fatty acids have been shown to have potential beneficial effects for
chronic diseases including cancer, insulin resistance and cardiovascular disease …

The Role of n-3 Polyunsaturated Fatty Acids in the Prevention and Treatment of Breast Cancer

J Liu, DWL Ma - nutrients, 2014 - mdpi.com
Breast cancer (BC) is the most common cancer among women worldwide. Dietary fatty
acids, especially n-3 polyunsaturated fatty acids (PUFA), are believed to play a role in …

Antitumor effect of oleic acid; mechanisms of action. A review

C Carrillo Pérez, MM Cavia Camarero… - … Hospitalaria, 2012, v …, 2012 - riubu.ubu.es
Introduction: The beneficial effects of oleic acid in cancer processes can no longer be
doubted, but little is known about the mechanisms of action behind this phenomenon. Aim …

Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer

LU Thompson, JM Chen, T Li, K Strasser-Weippl… - Clinical cancer …, 2005 - AACR
Purpose: Flaxseed, the richest source of mammalian lignan precursors, has previously been
shown to reduce the growth of tumors in rats. This study examined, in a randomized double …