Thyroid hormones (THs) play critical roles in the differentiation, growth, metabolism, and
physiological function of virtually all tissues. TH binds to receptors that are ligand …

Recent identification of new selenocysteine-containing proteins has revealed relationships
between the two trace elements selenium (Se) and iodine and the hormone network …

Several minerals and trace elements are essential for normal thyroid hormone metabolism,
eg, iodine, iron, selenium, and zinc. Coexisting deficiencies of these elements can impair …

Decreased serum thyroid hormone concentrations in severely ill patients were first reported
in the 1970s, but the functional meaning of the observed changes in thyroid hormone levels …

Several decades after the discovery of selenium as an essential trace element in vertebrates
approximately 20 eukaryotic and more than 15 prokaryotic selenoproteins containing the …

Thyroid hormones (THs) have important effects on cellular development, growth, and
metabolism. They bind to thyroid hormone receptors (TRs), TRα and TRβ, which belong to …

Micronutrients, mostly iodine and selenium, are required for thyroid hormone synthesis and
function. Iodine is an essential component of thyroid hormones and its deficiency is …

Hypothyroidism is a very common disorder worldwide, for which the usual treatment is
monotherapy with levothyroxine (L-T4). However, a number of patients treated with L-T4 …

The subventricular zone (SVZ) neural stem cell niche contains mixed populations of stem
cells, transit-amplifying cells, and migrating neuroblasts. Deciphering how endogenous …

After their initial discovery in the early 1950's, thyronamines (TAM), a class of endogenous
signalling compounds exhibiting structural similarity to the thyroid hormone L-thyroxine, are …