Lung ultrasound assessment of focal and non-focal lung morphology in patients with acute respiratory distress syndrome
C Pierrakos, MR Smit, L Pisani, F Paulus… - Frontiers in …, 2021 - frontiersin.org
Background: The identification of phenotypes based on lung morphology can be helpful to
better target mechanical ventilation of individual patients with acute respiratory distress …
better target mechanical ventilation of individual patients with acute respiratory distress …
Mangiferin mitigates lipopolysaccharide-induced lung injury by inhibiting NLRP3 inflammasome activation
N Li, R Xiong, R He, B Liu, B Wang… - Journal of Inflammation …, 2021 - Taylor & Francis
Scope Mangiferin (MF) is a natural phytopolyphenol, which displays potential
pharmacological properties involving antibacterial, anti-inflammation, antioxidant and anti …
pharmacological properties involving antibacterial, anti-inflammation, antioxidant and anti …
Integrative omics provide biological and clinical insights into acute respiratory distress syndrome
Purpose Acute respiratory distress syndrome (ARDS) is accompanied by a dysfunctional
immune-inflammatory response following lung injury, including during coronavirus disease …
immune-inflammatory response following lung injury, including during coronavirus disease …
[HTML][HTML] Electrical impedance tomography as a tool for monitoring mechanical ventilation. An introduction to the technique
D Maciejewski, Z Putowski, M Czok… - Advances in Medical …, 2021 - Elsevier
Electrical impedance tomography (EIT) is a non-invasive, radiation-free method of
diagnostics imaging, allowing for a bedside, real-time dynamic assessment of lung function …
diagnostics imaging, allowing for a bedside, real-time dynamic assessment of lung function …
Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCS1 axis
Y Su, JD Silva, D Doherty, DA Simpson, DJ Weiss… - Thorax, 2023 - thorax.bmj.com
Rationale A better understanding of the mechanism of action of mesenchymal stromal cells
(MSCs) and their extracellular vesicles (EVs) is needed to support their use as novel …
(MSCs) and their extracellular vesicles (EVs) is needed to support their use as novel …
The inflammatory lung microenvironment; a key mediator in MSC licensing
H Dunbar, DJ Weiss, S Rolandsson Enes, JG Laffey… - Cells, 2021 - mdpi.com
Recent clinical trials of mesenchymal stromal cell (MSC) therapy for various inflammatory
conditions have highlighted the significant benefit to patients who respond to MSC …
conditions have highlighted the significant benefit to patients who respond to MSC …
ACT001 suppressing M1 polarization against inflammation via NF-κB and STAT1 signaling pathways alleviates acute lung injury in mice
H Guo, Y Song, F Li, Y Fan, Y Li, C Zhang… - International …, 2022 - Elsevier
ACT001 has been shown to exhibit excellent antitumor and anti-fibrosis activities. However,
the role of ACT001 in acute lung injury (ALI) and the underlying mechanism remains largely …
the role of ACT001 in acute lung injury (ALI) and the underlying mechanism remains largely …
Identification of acute respiratory distress syndrome subphenotypes de novo using routine clinical data: a retrospective analysis of ARDS clinical trials
Objectives The acute respiratory distress syndrome (ARDS) is a heterogeneous condition,
and identification of subphenotypes may help in better risk stratification. Our study objective …
and identification of subphenotypes may help in better risk stratification. Our study objective …
Sacubitril/valsartan alleviates sepsis‐induced acute lung injury via inhibiting GSDMD‐dependent macrophage pyroptosis in mice
J Wang, J Li, A Lou, Y Lin, Q Xu, W Cui… - The FEBS …, 2023 - Wiley Online Library
Sepsis‐induced acute lung injury (ALI) is a life‐threatening disorder with intricate
pathogenesis. Macrophage pyroptosis reportedly plays a vital role in ALI. Although it has …
pathogenesis. Macrophage pyroptosis reportedly plays a vital role in ALI. Although it has …
Longitudinal phenotypes in patients with acute respiratory distress syndrome: a multi-database study
Background Previously identified phenotypes of acute respiratory distress syndrome (ARDS)
have been limited by a disregard for temporal dynamics. We aimed to identify longitudinal …
have been limited by a disregard for temporal dynamics. We aimed to identify longitudinal …