Asthma management in children
Asthma is a common, complex heterogeneous disease often beginning in early life and is
characterized by reversible airflow obstruction. The phenotypic differences that exist in …
characterized by reversible airflow obstruction. The phenotypic differences that exist in …
Biomarkers of therapy responsiveness in asthma: pitfalls and promises
SJH Vijverberg, L Koenderman… - Clinical & …, 2011 - Wiley Online Library
Asthma is one of the most common chronic diseases worldwide. There is a large inter‐
individual variability in response to asthma treatment. Most patients respond well to standard …
individual variability in response to asthma treatment. Most patients respond well to standard …
Childhood asthma exacerbations and the Arg16 β2-receptor polymorphism: a meta-analysis stratified by treatment
S Turner, B Francis, S Vijverberg, M Pino-Yanes… - Journal of Allergy and …, 2016 - Elsevier
Background The Gly-to-Arg substitution at the 16 position (rs1042713) in the β 2-
adrenoceptor gene (ADRB2) is associated with enhanced downregulation and uncoupling …
adrenoceptor gene (ADRB2) is associated with enhanced downregulation and uncoupling …
Tolerance & resistance to β2-agonist bronchodilators
RP Yim, AC Koumbourlis - Paediatric respiratory reviews, 2013 - Elsevier
For the past half-century, β 2-agonists have been the mainstay of treatment of the
bronchoconstriction associated with asthma. Although their usefulness in reversing acute …
bronchoconstriction associated with asthma. Although their usefulness in reversing acute …
Pharmacogenomics and pediatric asthmatic medications
C Lim, R Priefer - Journal of Respiration, 2022 - mdpi.com
Asthma is a respiratory condition often stemming from childhood, characterized by difficulty
breathing and/or chest tightness. Current treatment options for both adults and children …
breathing and/or chest tightness. Current treatment options for both adults and children …
Averaged versus individualized: pragmatic N-of-1 design as a method to investigate individual treatment response
Heterogeneous treatment effects represent a major issue for medicine as they undermine
reliable inference and clinical decision-making. To overcome the issue, the current vision of …
reliable inference and clinical decision-making. To overcome the issue, the current vision of …
Continuous Inhalation of Ipratropium Bromide for Acute Asthma Refractory to β2-agonist Treatment
AC Koumbourlis, C Mastropietro - The Journal of Pediatric …, 2015 - meridian.allenpress.com
To present the case of a patient with persistent bronchospasm, refractory to treatment with
β2-agonists, that resolved promptly with continuous inhalation of large dose (1000 mcg/hr) …
β2-agonists, that resolved promptly with continuous inhalation of large dose (1000 mcg/hr) …
Genetic polimorphisms and xenobiotic exposure in infantile asthma
RBM Soto, AA Medina - Gaceta Médica de México, 2011 - medigraphic.com
Together with industrial development in Mexico has come a major increase in the
generation of air pollutants. Some of these pollutants include compounds such as ozone …
generation of air pollutants. Some of these pollutants include compounds such as ozone …
[PDF][PDF] Die Rolle der DNA-Methylierung der Adenylatzyklase bei Rhinovirus-Infektionen vor dem Hintergrund der Asthmapathogenese
J Koch-Schultze - 2022 - zhb.uni-luebeck.de
Im Kindesalter ist Asthma bronchiale mit einem erhöhten Bedarf an Akutmedizin verbunden,
führt zu Fehltagen in der Schule und beeinträchtigt die Lebensqualität zB durch Vermeidung …
führt zu Fehltagen in der Schule und beeinträchtigt die Lebensqualität zB durch Vermeidung …
Pharmacogenetics of anti-inflammatory therapy in asthma: corticosteroids and leukotriene antagonists
ES Koster, AH Maitland-van der Zee… - Anti-Inflammatory & …, 2010 - ingentaconnect.com
Asthma is a chronic airway disease with a relatively high prevalence. Although the etiology
of asthma is still not fully clear, there are effective treatments available. The treatment …
of asthma is still not fully clear, there are effective treatments available. The treatment …