Simple Summary miRNAs are omnipresent short non-coding RNA molecules, which post-
transcriptionally fine-tune the expression of most protein-coding genes in health and …

Cancer pain may be the consequence of physical nerve compression by a growing tumor.
We employed a murine model to study whether gabapentin was able to regulate tumor …

Simple Summary Approximately 60% of all melanomas are associated with a constitutive
activating BRAF mutation. Inhibition of BRAF downstream signaling by targeted therapies …

MicroRNAs (miRNAs), which are small non-coding RNA molecules that post-
transcriptionally regulate the expression of target genes, control the vast majority of cellular …

Despite significant development of melanoma therapies, death rates remain high.
MicroRNAs, controlling posttranscriptionally gene expression, play role in development of …

The genetic landscape of melanoma resistance to targeted therapy with small molecules
inhibiting BRAF and MEK kinases is still largely undefined. In this study, we portrayed in …

Melanoma is the most aggressive form of skin cancer resulting from genetic mutations in
melanocytes. Several factors have been considered to be involved in melanoma …

Simple Summary We conducted a network analysis of microRNA–mRNA associations in
melanoma tissue and cell lines to identify the microRNAs central to melanoma biology and …

Background Melanoma is an aggressive skin cancer with increasing incidence worldwide.
The development of BRAF kinase inhibitors as targeted treatments for patients with BRAF …

Melanoma is a rare but highly lethal type of skin cancer whose incidence is increasing
globally. Melanoma is characterized by high resistance to therapy and relapse. Despite …