Actin participates in several essential processes in the cell nucleus. Even though the
presence of actin in the nucleus was proposed more than 30 years ago, nuclear processes …

Transcription in the nucleus of animal cells is performed by three distinct RNA polymerases
(RNAP), namely RNAPI, RNAPII, and RNAPIII. Among them, RNAPII is responsible for the …

The Hippo pathway effector TAZ promotes cellular growth, survival, and stemness through
regulating gene transcription. Recent studies suggest that TAZ liquid–liquid phase …

The mechanisms by which feeding and fasting drive rhythmic gene expression for
physiological adaptation to daily rhythm in nutrient availability are not well understood. Here …

RNA-binding proteins (RBPs) are a class of proteins known for their diverse roles in RNA
biogenesis, from regulating transcriptional processes in the nucleus to facilitating translation …

Termination of RNA polymerase II transcription frequently requires a poly (A) signal and
cleavage/polyadenylation factors. Recent work has shown that degradation of the …

The functional coupling of transcription and splicing has been reported both in vivo and in
vitro, but the molecular mechanisms governing these interactions remain largely unknown …

Nuclei of mammalian cells are highly organized and composed of distinct subnuclear
structures termed nuclear bodies. Paraspeckles are subnuclear structures that form around …

Transcription and pre-mRNA splicing are interdependent events. Although mechanisms
governing the effects of transcription on splicing are becoming increasingly clear, the means …

The presence of actin in the nucleus has been well established, and several studies have
implicated nuclear actin in transcriptional regulation,,. Neuronal Wiskott–Aldrich syndrome …