The neuropeptides calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-
activating polypeptide (PACAP) have emerged as mediators of migraine pathogenesis. Both …

Background Vestibular migraine is among the most common causes of recurrent vertigo in
the general population. Despite its prevalence and high impact on healthcare cost and …

Objective To determine the effect of erenumab, a human anti-calcitonin gene-related peptide
receptor monoclonal antibody, in patients with chronic migraine and medication overuse …

Migraine is a complex disorder characterized by recurrent episodes of headache, and is one
of the most prevalent and disabling neurological disorders. A key feature of migraine is that …

ABSTRACT Introduction: Calcitonin Gene-Related Peptide (CGRP) plays a crucial role in
migraine pathophysiology. A novel specific treatment strategy for the prevention of migraine …

Objective To provide the first clinical report that 2 calcitonin gene-related peptide (CGRP)
therapies, a small molecule CGRP receptor antagonist and an anti-CGRP receptor antibody …

Background The diagnosis of migraine is mainly clinical and self-reported, which makes
additional examinations unnecessary in most cases. Migraine can be subtyped into chronic …

Objective The objective of this study was to analyze the evolution of alpha and beta‐CGRP
circulating levels throughout CGRP monoclonal antibodies (mAbs) treatment in patients with …

Ocular surface neuropeptides are vital molecules primarily involved in maintaining ocular
surface integrity and homeostasis. They also serve as communication channels between the …

The neuropeptides CGRP (calcitonin gene-related peptide) and PACAP (pituitary adenylate
cyclase-activating polypeptide) have emerged as mediators of migraine, yet the potential …