Current status of PET tracers for the early diagnosis of Alzheimer's disease
Y Li, T Liu, Q Zeng, M Cui - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Positron emission tomography (PET) is a non-invasive imaging technology that can reveal
molecular alterations in the brains of Alzheimer's disease (AD) patients with high sensitivity …
molecular alterations in the brains of Alzheimer's disease (AD) patients with high sensitivity …
PET Imaging of Innate Immune Activation Using 11C Radiotracers Targeting GPR84
Chronic innate immune activation is a key hallmark of many neurological diseases and is
known to result in the upregulation of GPR84 in myeloid cells (macrophages, microglia, and …
known to result in the upregulation of GPR84 in myeloid cells (macrophages, microglia, and …
Aggregation-induced emission-active azines for chemosensing applications: A five-year update
Azines are an important class of compounds that display solvent-dependent fluorescence
emission depending upon the substituents in the aromatic scaffolds. They are affordable …
emission depending upon the substituents in the aromatic scaffolds. They are affordable …
Diagnostic and Therapeutic Radiopharmaceuticals: A “Hot” Topic
CW Lindsley, CE Müller… - ACS Pharmacology & …, 2023 - ACS Publications
Translational Science, we attempted to capture some of the advances in the field of
radiolabeled pharmaceuticals for imaging and therapy. Positron emission tomography (PET) …
radiolabeled pharmaceuticals for imaging and therapy. Positron emission tomography (PET) …
Coordination Chemistry of Sulfur-Containing Bifunctional Chelators: Toward in Vivo Stabilization of 64Cu PET Imaging Agents for Alzheimer's Disease
The broader utilization of 64Cu positron emission tomography (PET) imaging agents has
been hindered by the unproductive demetalation induced by bioreductants. To advance the …
been hindered by the unproductive demetalation induced by bioreductants. To advance the …
Screening of [18F]Florbetazine for Aβ Plaques and a Head-to-Head Comparison Study with [11C]Pittsburgh Compound-B ([11C]PiB) in Human Subjects
Y Li, X Zhang, H Zhao, Y Wang, D Zhang… - ACS Pharmacology & …, 2024 - ACS Publications
Positron emission tomography (PET) imaging of amyloid-β (Aβ) has emerged as a crucial
strategy for early diagnosis and monitoring of therapeutic advancements targeting Aβ. In our …
strategy for early diagnosis and monitoring of therapeutic advancements targeting Aβ. In our …
Development of an 18 F-labeled azobenzothiazole tracer for α-synuclein aggregates in the brain
J Wu, M Mao, J Yang, K Li, P Deng, J Zhong… - Organic & …, 2024 - pubs.rsc.org
Nuclear imaging of aggregated α-synuclein pathology is an urgent clinical need for
Parkinson's disease, yet promising tracers for brain α-synuclein aggregates are still rare. In …
Parkinson's disease, yet promising tracers for brain α-synuclein aggregates are still rare. In …
Radiolabeled imaging agents for Alzheimer's disease
J Wu, K Li, J Yang, M Mao, Y Cheng - iRADIOLOGY, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a chronic and progressive neurodegenerative disorder with long
preclinical and prodromal phases in older people. Molecular imaging is a promising …
preclinical and prodromal phases in older people. Molecular imaging is a promising …