Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment

Q Yang, M Ciebiera, MV Bariani, M Ali… - Endocrine …, 2022 - academic.oup.com
Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the
most common tumors in women worldwide. To date, no long-term or noninvasive treatment …

Epidemiology and risk factors of uterine fibroids

D Pavone, S Clemenza, F Sorbi, M Fambrini… - Best practice & research …, 2018 - Elsevier
Risk factors, both modifiable and non-modifiable, are associated with the development of
fibroids. These include age, race, endogenous and exogenous hormonal factors, obesity …

Uterine fibroids

EA Stewart, SK Laughlin-Tommaso… - Nature reviews Disease …, 2016 - nature.com
Uterine fibroids (also known as leiomyomas or myomas) are common clonal neoplasms of
the uterus. Fibroids have both smooth muscle and fibroblast components, in addition to a …

Uterine fibroids: burden and unmet medical need

A Al-Hendy, ER Myers, E Stewart - Seminars in reproductive …, 2017 - thieme-connect.com
Uterine fibroids affect a wide cross-section of the population, with prevalence, symptom
severity, and overall disease burden generally higher among black women, likely due to …

Uterine fibroids: hiding in plain sight

EA Stewart, RA Nowak - Physiology, 2022 - journals.physiology.org
Uterine fibroids (leiomyomas) are present in> 75% of women and can cause serious
morbidity. They are by far the leading cause of hysterectomy. Fibroids are a complex mixture …

Role of transforming growth factor β in uterine fibroid biology

M Ciebiera, M Włodarczyk, M Wrzosek… - International Journal of …, 2017 - mdpi.com
Uterine fibroids (UFs) are benign tumors of the female genital tract made of the smooth
muscle of the uterus. UF growth depends mostly on the influence of the steroid hormones …

Vitamin D and uterine fibroids—review of the literature and novel concepts

M Ciebiera, M Włodarczyk, M Ciebiera… - International Journal of …, 2018 - mdpi.com
This article provides a detailed review of current knowledge on the role of vitamin D and its
receptor in the biology and management of uterine fibroids (UFs). Authors present ideas for …

Update on the role and regulatory mechanism of extracellular matrix in the pathogenesis of uterine fibroids

Q Yang, A Al-Hendy - International Journal of Molecular Sciences, 2023 - mdpi.com
Uterine fibroids (UFs), also known as leiomyomas, are benign tumors of the myometrium
affecting over 70% of women worldwide, particularly women of color. Although benign, UFs …

[HTML][HTML] Influence of vitamin D and transforming growth factor β3 serum concentrations, obesity, and family history on the risk for uterine fibroids

M Ciebiera, M Włodarczyk, A Słabuszewska-Jóźwiak… - Fertility and …, 2016 - Elsevier
Objective To evaluate the influence of 25-hydroxyvitamin D and transforming growth factor
β3 (TGF-β3) serum concentrations, weight, and family history on the risk of developing …

The role of tumor necrosis factor α in the biology of uterine fibroids and the related symptoms

M Ciebiera, M Włodarczyk, M Zgliczyńska… - International journal of …, 2018 - mdpi.com
Uterine fibroids (UFs) are the most common benign tumors of the female genital tract. The
incidence of UFs has been estimated at 25–80% depending on selected population. The …