Role of NRF2 in ovarian cancer
G Tossetta, S Fantone, E Montanari, D Marzioni… - Antioxidants, 2022 - mdpi.com
Among gynaecologic malignancies, ovarian cancer is one of the most dangerous, with a
high fatality rate and relapse due to the occurrence of chemoresistance. Many researchers …
high fatality rate and relapse due to the occurrence of chemoresistance. Many researchers …
Mitochondrial dysfunction and oxidative stress caused by cryopreservation in reproductive cells
Mitochondria, fundamental organelles in cell metabolism, and ATP synthesis are
responsible for generating reactive oxygen species (ROS), calcium homeostasis, and cell …
responsible for generating reactive oxygen species (ROS), calcium homeostasis, and cell …
Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport
J Florido, L Martinez‐Ruiz… - Journal of Pineal …, 2022 - Wiley Online Library
The oncostatic effects of melatonin correlate with increased reactive oxygen species (ROS)
levels, but how melatonin induces this ROS generation is unknown. In the present study, we …
levels, but how melatonin induces this ROS generation is unknown. In the present study, we …
An updated review of mechanistic potentials of melatonin against cancer: pivotal roles in angiogenesis, apoptosis, autophagy, endoplasmic reticulum stress and …
Cancers are serious life-threatening diseases which annually are responsible for millions of
deaths across the world. Despite many developments in therapeutic approaches for affected …
deaths across the world. Despite many developments in therapeutic approaches for affected …
Understanding the mechanism of action of melatonin, which induces ROS production in cancer cells
J Florido, C Rodriguez-Santana, L Martinez-Ruiz… - Antioxidants, 2022 - mdpi.com
Reactive oxygen species (ROS) constitute a group of highly reactive molecules that have
evolved as regulators of important signaling pathways. In this context, tumor cells have an …
evolved as regulators of important signaling pathways. In this context, tumor cells have an …
Melatonin mitigates cisplatin-induced ovarian dysfunction via altering steroidogenesis, inflammation, apoptosis, oxidative stress, and PTEN/PI3K/Akt/mTOR/AMPK …
A Al-Shahat, MAE Hulail, NMM Soliman, T Khamis… - Pharmaceutics, 2022 - mdpi.com
Ovarian damage and fertility impairment are major side effects of chemotherapy in pre-
menopausal cancer patients. Cisplatin is a widely used chemotherapeutic drug. The present …
menopausal cancer patients. Cisplatin is a widely used chemotherapeutic drug. The present …
Nutritional management of thyroiditis of Hashimoto
Y Danailova, T Velikova, G Nikolaev, Z Mitova… - International journal of …, 2022 - mdpi.com
Since the thyroid gland is one of the organs most affected by autoimmune processes, many
patients with thyroiditis of Hashimoto (TH) seek medical advice on lifestyle variance and …
patients with thyroiditis of Hashimoto (TH) seek medical advice on lifestyle variance and …
Natural cryoprotective and cytoprotective agents in cryopreservation: A focus on melatonin
G Marcantonini, D Bartolini, L Zatini, S Costa… - Molecules, 2022 - mdpi.com
Cryoprotective and cytoprotective agents (Cytoprotective Agents) are fundamental
components of the cryopreservation process. This review presents the essentials of the …
components of the cryopreservation process. This review presents the essentials of the …
Melatonin as an antioxidant and immunomodulator in atopic dermatitis—A new look on an old story: A Review
AK Jaworek, JC Szepietowski, P Hałubiec… - Antioxidants, 2021 - mdpi.com
Atopic dermatitis (AD) is common inflammatory dermatosis, typically with chronic and
recurrent course, which significantly reduces the quality of life. Sleep disturbances are …
recurrent course, which significantly reduces the quality of life. Sleep disturbances are …
The dual angiogenesis effects via Nrf2/HO-1 signaling pathway of melatonin nanocomposite scaffold on promoting diabetic bone defect repair
T Chen, Z Wu, Q Hou, Y Mei, K Yang, J Xu… - International Journal of …, 2024 - Taylor & Francis
Purpose Given the escalating prevalence of diabetes, the demand for specific bone graft
materials is increasing, owing to the greater tendency towards bone defects and more …
materials is increasing, owing to the greater tendency towards bone defects and more …