Our previous research has shown that melatonin (MLT) can reduce cryopreserved ovarian
damage in mice. Yet, the molecular mechanism of MLT protection is still unclear. Some …

Oxidative and dicarbonyl stress, driven by excess accumulation of glycolytic intermediates in
cells that are highly permeable to glucose in the absence of effective insulin activity, appear …

In this study, the effects of daily melatonin supplementation (2 mg/kg) at the late gestational
stage on the reproductive performance of the sows have been investigated. This treatment …

Oxidative stress occurs when there is an imbalance between the production of reactive
oxygen species (ROS) and the body's antioxidant defenses. It poses a significant threat to …

Despite the advances in cryopreservation procedures, the developmental rate of frozen-
thawed oocytes is still lower compared to their fresh counterparts. Mechanical damage by …

Vitrification is a promising method for ovarian cortex preservation, however, oxidative stress
resulting from excessive free radical production can cause irreversible damage to the ovary …

Studies have shown that stress caused by lack of physical activity disrupts the normal
pattern of glucocorticoid secretion which adversely affects the reproductive axis. We studied …

Childhood cancer incidence, especially in high-income countries, has led to a focus on
preserving fertility in this vulnerable population. The common treatments, such as radiation …

We investigated using histochemistry and immunohistochemistry ovarian damage caused
by nonylphenol (NP) and the protective effect of melatonin treatment of NP induced ovarian …

Ovarian tissue cryopreservation transplantation (OTCT) is the most flexible option to
preserve fertility in women and children with cancer. However, OTCT is associated with …