Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart …
K Musunuru, KT Hickey, SM Al-Khatib… - Circulation …, 2015 - Am Heart Assoc
The American Heart Association makes every effort to avoid any actual or potential conflicts
of interest that may arise as a result of an outside relationship or a personal, professional, or …
of interest that may arise as a result of an outside relationship or a personal, professional, or …
[HTML][HTML] The multi-faceted aspects of the complex cardiac Nav1. 5 protein in membrane function and pathophysiology
The aim of this mini-review is to draw together the main concepts and findings that have
emerged from recent studies of the cardiac channel protein Na v 1.5. This complex protein is …
emerged from recent studies of the cardiac channel protein Na v 1.5. This complex protein is …
Genetics of channelopathies associated with sudden cardiac death
O Campuzano, G Sarquella-Brugada… - … Science and Practice, 2015 - qscience.com
Recent technological advances in cardiology have resulted in new guidelines for the
diagnosis, treatment and prevention of diseases. Despite these improvements, sudden …
diagnosis, treatment and prevention of diseases. Despite these improvements, sudden …
Characterization of SEMA3A-Encoded Semaphorin as a Naturally Occurring Kv4.3 Protein Inhibitor and its Contribution to Brugada Syndrome
NJ Boczek, D Ye, EK Johnson, W Wang… - Circulation …, 2014 - Am Heart Assoc
Rationale: Semaphorin 3A (SEMA3A)-encoded semaphorin is a chemorepellent that
disrupts neural patterning in the nervous and cardiac systems. In addition, SEMA3A has an …
disrupts neural patterning in the nervous and cardiac systems. In addition, SEMA3A has an …
iPSC-cardiomyocyte models of Brugada syndrome—achievements, challenges and future perspectives
A Nijak, J Saenen, AJ Labro, D Schepers… - International journal of …, 2021 - mdpi.com
Brugada syndrome (BrS) is an inherited cardiac arrhythmia that predisposes to ventricular
fibrillation and sudden cardiac death. It originates from oligogenic alterations that affect …
fibrillation and sudden cardiac death. It originates from oligogenic alterations that affect …
The role of semaphorins in cardiovascular diseases: Potential therapeutic targets and novel biomarkers.
Z Yin, J Zhang, S Xu, J Liu, Y Xu, J Yu… - … : Official Publication of …, 2022 - europepmc.org
Semaphorins (Semas), which belongs to the axonal guidance molecules, include 8 classes
and could affect axon growth in the nervous system. Recently, semaphorins were found to …
and could affect axon growth in the nervous system. Recently, semaphorins were found to …
Broad electrocardiogram syndromes spectrum: from common emergencies to particular electrical heart disorders
A Balta, A Ceasovschih, V Șorodoc… - Journal of Personalized …, 2022 - mdpi.com
Electrocardiogram (ECG) still remains a very useful diagnostic method in modern
cardiology. Its broad availability, noninvasiveness and good sensitivity explain why it plays a …
cardiology. Its broad availability, noninvasiveness and good sensitivity explain why it plays a …
Mutation in S6 domain of HCN4 channel in patient with suspected Brugada syndrome modifies channel function
S Biel, M Aquila, B Hertel, A Berthold… - … -European Journal of …, 2016 - Springer
Diseases such as the sick sinus and the Brugada syndrome are cardiac abnormalities,
which can be caused by a number of genetic aberrances. Among them are mutations in …
which can be caused by a number of genetic aberrances. Among them are mutations in …
[HTML][HTML] Attendance-related healthcare resource utilisation and costs in patients with Brugada syndrome in Hong Kong: a retrospective cohort study
Understanding health care resource utilisation and its associated costs are important for
identifying areas of improvement regarding resource allocations. However, there is limited …
identifying areas of improvement regarding resource allocations. However, there is limited …
Sudden cardiac death—a new insight into potentially fatal genetic markers
Sudden cardiac death (SCD) is an unexpected and dramatic event. It draws special attention
especially in young, seemingly healthy athletes. Our scientific paper is based on the death of …
especially in young, seemingly healthy athletes. Our scientific paper is based on the death of …