Unmasking of Brugada syndrome by lamotrigine in a patient with pre-existing epilepsy: A case report with review of the literature

H Omer, MH Omer, AR Alyousef… - Frontiers in …, 2022 - frontiersin.org
Brugada syndrome is an inherited cardiac channelopathy arising from mutations in voltage-
gated cardiac sodium channels. Idiopathic epilepsy portrays a coalescent underlying …

Farmakoterapi Penyakit Paru Obstruksi Kronik (PPOK)

E Kristiningrum - Cermin Dunia Kedokteran, 2019 - cdkjournal.com
Abstract Penyakit Paru Obstruksi Kronik (PPOK) adalah penyakit yang umum, dapat dicegah
dan diobati, ditandai dengan gejala pernapasan persisten dan keterbatasan aliran udara …

Mutational analysis of mitochondrial DNA in Brugada syndrome

L Stocchi, E Polidori, L Potenza, MBL Rocchi… - Cardiovascular …, 2016 - Elsevier
Abstract Background Brugada syndrome (BrS) is a primary electrical disease associated
with an increased risk of sudden cardiac death due to ventricular fibrillation. This pathology …

Blockade of CaMKII depresses conduction preferentially in the right ventricular outflow tract and promotes ischemic ventricular fibrillation in the rabbit heart

M Warren, KJ Sciuto, TG Taylor… - American Journal …, 2017 - journals.physiology.org
Calcium/calmodulin-dependent protein kinase II (CaMKII) regulates the principle ion
channels mediating cardiac excitability and conduction, but how this regulation translates to …

Conduction in the right and left ventricle is differentially regulated by protein kinases and phosphatases: implications for arrhythmogenesis

AV Zaitsev, NS Torres, KM Cawley… - American Journal …, 2019 - journals.physiology.org
The “stress” kinases cAMP-dependent protein kinase (PKA) and calcium/calmodulin-
dependent protein kinase II (CaMKII), phosphorylate the Na+ channel Nav1. 5 subunit to …

Molecular autopsy of desmosomal protein plakophilin‐2 in sudden unexplained nocturnal death syndrome

L Huang, S Tang, L Peng, Y Chen… - Journal of forensic …, 2016 - Wiley Online Library
Abstract Plakophilin‐2 (PKP 2) variants could produce a phenotype of Brugada syndrome
(BrS), which seems to be most likely the same allelic disorder as some sudden unexplained …

Low serum levels of eicosapentaenoic acid and docosahexaenoic acid are risk factors for cardiogenic syncope in patients with Brugada syndrome

S Yagi, T Soeki, K Aihara, D Fukuda, T Ise… - International Heart …, 2017 - jstage.jst.go.jp
The n-3 polyunsaturated fatty acids (PUFAs), including eicosapentaenoic acid (EPA) and
docosahexaenoic acid (DHA), have antiarrhythmic effects, possibly via modulation of the …

Sudden cardiac death in Brugada syndrome

N Kabra, R Gupta, WS Aronow… - Cardiology in …, 2020 - journals.lww.com
The Brugada syndrome is an inherited channelopathy that alters the main transmembrane
ion currents that constitute the cardiac action potential. These changes not only modify the …

Electrocardiographic assessment and genetic analysis in neonates: a current topic of discussion

G Sarquella-Brugada, S Cesar… - Current Cardiology …, 2019 - ingentaconnect.com
Background: Sudden death of a newborn is a rare entity, which may be caused by genetic
cardiac arrhythmias. Among these diseases, Long QT syndrome is the most prevalent …

Functional analysis of SCN5A genetic variants associated with Brugada syndrome

VB Mikhailova, AV Karpushev, VD Vavilova… - Cardiology, 2022 - karger.com
Background: Brugada syndrome (BrS) is a rare inherited cardiac arrhythmia with increased
risk of sudden cardiac death. Mutations in gene SCN5A, which encodes the α-subunit of …