[PDF][PDF] Δ9-Tetrahydrocannabinol (THC): The major psychoactive component is of botanical origin

RB Malabadi, KP Kolkar… - International Journal of …, 2023 - journalijisr.com
This review paper highlights the medicinal value of Cannabis sativa belongs to
Cannabaceae family. The use of the female inflorescence of Medical Cannabis sativa …

Measuring disturbance of the endocannabinoid system in psychosis: a systematic review and meta-analysis

A Minichino, M Senior, N Brondino, SH Zhang… - JAMA …, 2019 - jamanetwork.com
Importance The endocannabinoid system (ECS) is a lipid-based endogenous signaling
system. Its relevance to psychosis is through the association between cannabis use and the …

Synthetic pot: not your grandfather's marijuana

BM Ford, S Tai, WE Fantegrossi, PL Prather - Trends in pharmacological …, 2017 - cell.com
In the early 2000s in Europe and shortly thereafter in the USA, it was reported that
'legal'forms of marijuana were being sold under the name K2 and/or Spice. Active …

[HTML][HTML] Wonder or evil?: multifaceted health hazards and health benefits of Cannabis sativa and its phytochemicals

S Datta, PC Ramamurthy, U Anand, S Singh… - Saudi journal of …, 2021 - Elsevier
Cannabis sativa, widely known as 'Marijuana'poses a dilemma for being a blend of both
good and bad medicinal effects. The historical use of Cannabis for both medicinal and …

Cancer cachexia: a multifactoral disease that needs a multimodal approach

R Stubbins, EH Bernicker… - Current opinion in …, 2020 - journals.lww.com
Cancer cachexia is a complex multifactorial condition that can only be successfully
managed and treated with a multimodal approach that involves a multidisciplinary team that …

Characterization of structurally novel G protein biased CB1 agonists: Implications for drug development

BM Ford, LN Franks, S Tai, WE Fantegrossi… - Pharmacological …, 2017 - Elsevier
The human cannabinoid subtype 1 receptor (hCB 1 R) is highly expressed in the CNS and
serves as a therapeutic target for endogenous ligands as well as plant-derived and synthetic …

[HTML][HTML] The endocannabinoid system, our universal regulator

CA Sallaberry, L Astern - Journal of Young Investigators, 2018 - jyi.org
The endocannabinoid system (ECS) plays a very important role in the human body for our
survival. This is due to its ability to play a critical role in maintaining the homeostasis of the …

Development of the High-Affinity Carborane-Based Cannabinoid Receptor Type 2 PET Ligand [18F]LUZ5-d8

L Ueberham, D Gündel, M Kellert… - Journal of Medicinal …, 2023 - ACS Publications
The development of cannabinoid receptor type 2 (CB2R) radioligands for positron emission
tomography (PET) imaging was intensively explored. To overcome the low metabolic …

[HTML][HTML] A cannabinoid hypothesis of schizophrenia: pathways to psychosis

R Little, D D'Mello - Innovations in clinical neuroscience, 2022 - ncbi.nlm.nih.gov
Background Observations regarding psychostimulant and psychedelic drug-induced
psychotic states led to the dopamine, serotonin, and glutamate hypotheses of schizophrenia …

Diverse role of endocannabinoid system in mammalian male reproduction

TS Sayed, NH Balasinor, K Nishi - Life Sciences, 2021 - Elsevier
Endocannabinoid system (ECS) is known for its modulatory role in numerous physiological
processes in the body. Endocannabinoids (eCBs) are endogenous lipid molecules which …