Functions, Mechanisms, and therapeutic applications of the inositol pyrophosphates 5PP-InsP5 and InsP8 in mammalian cells

J Qi, L Shi, L Zhu, Y Chen, H Zhu, W Cheng… - Journal of …, 2024 - Springer
Water-soluble myo-inositol phosphates have long been characterized as second
messengers. The signaling properties of these compounds are determined by the number …

Interactions of analgesics with cisplatin: Modulation of anticancer efficacy and potential organ toxicity

A El-Sheikh, Z Khired - Medicina, 2021 - mdpi.com
Cisplatin (CDDP), one of the most eminent cancer chemotherapeutic agents, has been
successfully used to treat more than half of all known cancers worldwide. Despite its …

[HTML][HTML] Suppressing MDSC infiltration in tumor microenvironment serves as an option for treating ovarian cancer metastasis

Y Li, Q Zhang, M Wu, P Zhang, L Huang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
It is still a big puzzle how ovarian cancer cells and the tumor microenvironment (TME) attract
lymphocytes infiltration for facilitating metastasis, a leading cause of death from …

PPIP5K2 promotes colorectal carcinoma pathogenesis through facilitating DNA homologous recombination repair

CH Cao, H Ling, K Han, XP Lu, MY Cai, JH Cao… - Oncogene, 2021 - nature.com
Colorectal carcinoma (CRC) is the second most deadly cancer worldwide. Therapies that
take advantage of DNA repair defects have been explored in various tumors but not yet …