Pertussis is a severe respiratory infection caused by Bordetella pertussis, and in 2008,
pertussis was associated with an estimated 16 million cases and 195,000 deaths globally …

Although the introduction of universal pertussis immunisation in infants has greatly reduced
the number of reported cases in infants and young children, disease incidence has been …

BACKGROUND: The relative contribution of different categories of contact in transmitting
pertussis to very young infants, who experience the most severe morbidity, is the most …

Bordetella pertussis–the cause of pertussis or whooping cough–is an exclusively human
pathogen. Disease elimination by vaccination should, therefore, be possible, but has proved …

Pertussis causes nearly 300 000 deaths in children every year. Most deaths take place in
developing countries, but the infection remains a priority everywhere. Pertussis vaccination …

Background In many countries, the reported pertussis has increased despite high
vaccination coverage. However, accurate determination of the burden of disease is …

OBJECTIVES: Because young infants are at highest risk of pertussis complications, this
study assessed whether neonatal acellular pertussis (aP) vaccination could provide earlier …

OBJECTIVES: To evaluate the safety and immunogenicity of an additional birth dose of
diphtheria, tetanus, and acellular pertussis vaccine (DTaP). STUDY DESIGN: Fifty infants …

Vaccination against pertussis has resulted in reduction of the infection pressure of
Bordetella pertussis (partial herd immunity), but the circulation of B. pertussis has persisted …

Despite high vaccination coverage, over the last fifteen years there has been a worldwide
resurgence of B. pertussis infection. While classical pertussis in the prevaccine era was …