p62/SQSTM1, encoded by gene SQSTM1, is widely known as an adaptor protein of
selective autophagy to promote aggregate-prone proteins for degradation. It is also a stress …

Abstract NF-E2–related factor 2 (NRF2) is a master transcriptional regulator that integrates
cellular stress responses and is negatively regulated by Kelch-like ECH-associated protein …

Human dipeptidyl-peptidase III (hDPP III) is a zinc-dependent hydrolase cleaving dipeptides
off the N-termini of various bioactive peptides. Thus, the enzyme is likely involved in a …

Opioid peptides are involved in various essential physiological processes, most notably
nociception. Dipeptidyl peptidase III (DPP III) is one of the most important enkephalin …

Abstract Dipeptidyl-peptidase 3 (DPP3) plays a key role in regulating apoptosis, oxidative
stress and inflammation under various pathological conditions, however, whether DPP3 …

Pancreatic cancer is a disease in which deregulation of signaling pathways plays a key role,
thus searching for their novel modulators is a promising therapeutic strategy. Hence, in this …

Dipeptidyl-peptidases III (DPP III) are zinc-dependent enzymes that specifically cleave the
first two amino acids from the N terminus of different length peptides. In mammals, DPP III is …

Background Extensive research on p62 has established its role in oxidative stress, protein
degradation and in several diseases such as Paget's disease of the bone, frontotemporal …

The ataxia telangiectasia mutated (ATM) protein kinase is best known as a master regulator
of the DNA damage response. However, accumulating evidence has unveiled an equally …

Context: The β-amyloid (Aβ) peptide aggregation with accompanying oxidative stress plays
the major role in the pathogenesis of Alzheimer's disease (AD). Some natural compounds …