A bottom-up view of antimicrobial resistance transmission in developing countries

OO Ikhimiukor, EE Odih, P Donado-Godoy… - Nature …, 2022 - nature.com
Antimicrobial resistance (AMR) is tracked most closely in clinical settings and high-income
countries. However, resistant organisms thrive globally and are transmitted to and from …

Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward

AK Nanayakkara, HW Boucher… - CA: a cancer journal …, 2021 - Wiley Online Library
Infection is the second leading cause of death in patients with cancer. Loss of efficacy in
antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing …

Mortality, length of stay, and healthcare costs associated with multidrug-resistant bacterial infections among elderly hospitalized patients in the United States

RE Nelson, D Hyun, A Jezek… - Clinical Infectious …, 2022 - academic.oup.com
Background This study reports estimates of the healthcare costs, length of stay, and mortality
associated with infections due to multidrug-resistant bacteria among elderly individuals in …

Fecal microbiota transplantation promotes reduction of antimicrobial resistance by strain replacement

MH Woodworth, RE Conrad, M Haldopoulos… - Science translational …, 2023 - science.org
Multidrug-resistant organism (MDRO) colonization is a fundamental challenge in
antimicrobial resistance. Limited studies have shown that fecal microbiota transplantation …

The economic burden of antibiotic resistance: A systematic review and meta-analysis

AN Poudel, S Zhu, N Cooper, P Little, C Tarrant… - Plos one, 2023 - journals.plos.org
Introduction Antibiotic resistance (ABR) has substantial global public health concerns. This
systematic review aimed to synthesise recent evidence estimating the economic burden of …

Impact of SARS-CoV-2 epidemic on antimicrobial resistance: a literature review

FV Segala, DF Bavaro, F Di Gennaro, F Salvati… - Viruses, 2021 - mdpi.com
Antimicrobial resistance is an urgent threat to public health and global development; in this
scenario, the SARS-CoV2 pandemic has caused a major disruption of healthcare systems …

Re-establishing the utility of tetracycline-class antibiotics for current challenges with antibiotic resistance

KL LaPlante, A Dhand, K Wright, M Lauterio - Annals of Medicine, 2022 - Taylor & Francis
The progressive increase in antibiotic resistance in recent decades calls for urgent
development of new antibiotics and antibiotic stewardship programs to help select …

Time-to-antibiotics and clinical outcomes in patients with sepsis and septic shock: a prospective nationwide multicenter cohort study

Y Im, D Kang, RE Ko, YJ Lee, SY Lim, S Park, SJ Na… - Critical Care, 2022 - Springer
Background Timely administration of antibiotics is one of the most important interventions in
reducing mortality in sepsis. However, administering antibiotics within a strict time threshold …

Klebsiella pneumoniae bacteremia mortality: a systematic review and meta-analysis

D Li, X Huang, H Rao, H Yu, S Long, Y Li… - Frontiers in Cellular and …, 2023 - frontiersin.org
Objective To analyze the mortality rate of patients with Klebsiella pneumoniae bacteremia
(KPB) and the impact of extended spectrum beta-lactamase (ESBL) producing or …

Photoactive MOF-derived bimetallic silver and cobalt nanocomposite with enhanced antibacterial activity

D Kim, KW Park, JT Park, I Choi - ACS applied materials & …, 2023 - ACS Publications
Conventional antibiotic-based treatment of bacterial infections remains one of the most
difficult challenges in medicine because of the threat of multidrug resistance caused by …