Abstract In recent years, 5-methylcytosine (m5C) RNA modification has emerged as a key
player in regulating RNA metabolism and function through coding as well as non-coding …

Genomic imprinting is an epigenetic phenomenon that results in monoallelic gene
expression according to parental origin. It has long been established that imprinted genes …

Glomerular podocytes are highly specialized cells with a complex cytoarchitecture. Their
most prominent features are interdigitated foot processes with filtration slits in between …

First identified as cell cycle inhibitors mediating the growth inhibitory cues of upstream
signaling pathways, the cyclin-CDK inhibitors of the Cip/Kip family p21Cip1, p27Kip1, and …

Hematopoietic stem cells (HSCs) give rise to all lineages of blood cells. Because HSCs must
persist for a lifetime, the balance between their proliferation and quiescence is carefully …

Curcumin has been shown to have a wide variety of therapeutic effects, ranging from anti-
inflammatory, chemopreventive, anti-proliferative, and anti-metastatic. This review provides …

Breakdown or absence of vascular oxygen delivery is a hallmark of many common human
diseases, including cancer, myocardial infarction, and stroke. The chief mediator of hypoxic …

The visceral glomerular epithelial cell, also called podocyte, is a terminally differentiated cell
that lines the outer aspect of the glomerular basement membrane (GBM). It therefore forms …

The identification of target mRNAs is a key step for assessing the role of aberrantly
expressed microRNAs in human cancer. MiR-221 is upregulated in human hepatocellular …

The skeleton is a dynamic tissue continuously adapting to mechanical stimuli. Although
matrix‐embedded osteocytes are considered as the key mechanoresponsive bone cells, all …