Ovarian cancer is an aggressive disease that is frequently detected at advanced stages and
is initially very responsive to platinum-based chemotherapy. However, the majority of …

Ovarian carcinomas represent a heterogeneous group of neoplasms consisting of separate
entities with distinct risk factors, precursor lesions, pathogenesis, patterns of spread …

Summary The Gynecologic Cancer InterGroup (GCIG) sixth Ovarian Cancer Conference on
Clinical Research was held virtually in October, 2021, following published consensus …

Background Epithelial ovarian cancer (OC) is a heterogenous disease consisting of five
major histologically distinct subtypes: high-grade serous (HGSOC), low-grade serous …

Simple Summary Historically, cancers presenting with their main tumor mass in the ovary
have been classified as ovarian carcinomas (a concise term for epithelial ovarian cancer) …

Ovarian carcinoma (OC) is an umbrella term for multiple distinct diseases (histotypes), each
with their own developmental origins, clinical behaviour and molecular profile. Accordingly …

Following a period of slow progress, the completion of genome sequencing and the
paradigm shift relative to the cell of origin for high grade serous ovarian cancer (HGSOC) led …

Ovarian clear cell (OCCC) and endometrioid (EnOC) carcinomas are often subsumed under
the umbrella term “endometriosis-associated ovarian cancer”(EAOC), since they frequently …

Ovarian cancer has the highest mortality of all of the gynecological malignancies. There are
several distinct histotypes of this malignancy characterized by specific molecular events and …

Simple Summary Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a
multifunctional tumor suppressor with protein-and lipid-phosphatase activities. The …