Osteoporosis is a progressive, systemic bone disorder characterized by loss of bone mass
and microstructure, leading to reduced bone strength and increased risk of fracture. It is …

Background There is conflicting evidence regarding the association between decreased
bone mineral density (BMD) and atherosclerosis. To this end, we performed a systematic …

Fractures across the stages of chronic kidney disease (CKD) could be due to osteoporosis,
some form of renal osteodystrophy defined by specific quantitative histomorphometry or …

Excessive bone resorption by osteoclasts (OCs) can result in serious clinical outcomes,
including bone loss that may weaken skeletal or periodontal strength. Proper bone …

Receptor activator of nuclear factor-κB ligand (RANKL) has been actively pursued as a
therapeutic target for osteoporosis, given that RANKL is the master mediator of bone …

Objectives Insulin‐like growth factor‐binding protein 7 (IGFBP7) is a low‐affinity insulin
growth factor (IGF) binder that may play an important role in bone metabolism. We …

During the past 15 years there has been an expansion of our knowledge of the cellular and
molecular mechanisms regulating bone remodeling that identified new signaling pathways …

The delivery of novel bioactive scaffolds for the repair of bone defects remains a prominent
challenge worldwide. Currently osteoporosis, a disease caused by low bone mineral density …

Increased bone resorption and enhanced risk of osteoporotic fractures are often reported in
patients with diseases having immune system involvement, mainly inflammatory rheumatic …

Peptidomimetics, the mimics of natural peptides are considered as promising therapeutics
with potential applications in modern medicine. Among the various structural variants of …