Exosomes as mediators of intercellular crosstalk in metabolism
Exosomes are nanoparticles secreted by all cell types and are a large component of the
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …
Extracellular vesicles and particles impact the systemic landscape of cancer
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …
Re-engineering extracellular vesicles as smart nanoscale therapeutics
In the past decade, extracellular vesicles (EVs) have emerged as a key cell-free strategy for
the treatment of a range of pathologies, including cancer, myocardial infarction, and …
the treatment of a range of pathologies, including cancer, myocardial infarction, and …
Exosomes derived from osteogenic tumor activate osteoclast differentiation and concurrently inhibit osteogenesis by transferring COL1A1‐targeting miRNA‐92a‐1‐5p
In patients with prostate cancer (PCa), bone lesions appear osteoblastic in radiographs;
however, pathological fractures frequently occur in PCa patients, and bone resorption is …
however, pathological fractures frequently occur in PCa patients, and bone resorption is …
Extracellular vesicles: potential roles in regenerative medicine
OG De Jong, BWM Van Balkom… - Frontiers in …, 2014 - frontiersin.org
Extracellular vesicles (EV) consist of exosomes, which are released upon fusion of the
multivesicular body with the cell membrane, and microvesicles, which are released directly …
multivesicular body with the cell membrane, and microvesicles, which are released directly …
Mass-spectrometry-based molecular characterization of extracellular vesicles: lipidomics and proteomics
This review discusses extracellular vesicles (EVs), which are submicron-scale, anuclear,
phospholipid bilayer membrane enclosed vesicles that contain lipids, metabolites, proteins …
phospholipid bilayer membrane enclosed vesicles that contain lipids, metabolites, proteins …
Exosome: a novel approach to stimulate bone regeneration through regulation of osteogenesis and angiogenesis
Y Qin, R Sun, C Wu, L Wang, C Zhang - International journal of molecular …, 2016 - mdpi.com
The clinical need for effective bone regeneration therapy remains in huge demands.
However, the current “gold standard” treatments of autologous and allogeneic bone grafts …
However, the current “gold standard” treatments of autologous and allogeneic bone grafts …
The roles of bone‐derived exosomes and exosomal micro RNA s in regulating bone remodelling
Y Xie, Y Chen, L Zhang, W Ge… - Journal of cellular and …, 2017 - Wiley Online Library
Pathological destructive bone diseases are primarily caused by the failure of a lifelong self‐
renewal process of the skeletal system called bone remodelling. The mechanisms …
renewal process of the skeletal system called bone remodelling. The mechanisms …
Systematic review of targeted extracellular vesicles for drug delivery–considerations on methodological and biological heterogeneity
JM Gudbergsson, K Jønsson, JB Simonsen… - Journal of Controlled …, 2019 - Elsevier
The idea of using extracellular vesicles (EVs) for targeted drug delivery was first introduced
in 2011 and has since then gained increasing attention as promising new candidates in the …
in 2011 and has since then gained increasing attention as promising new candidates in the …