Obesity and its comorbidities, including type 2 diabetes mellitus, cardiovascular disease,
heart failure and non-alcoholic liver disease are a major health and economic burden with …

Over the past two decades, whole food supplementation strategies have been leveraged to
target mental health. In addition, there has been increasing attention on the ability of gut …

Regenerating family member gamma, Reg3γ (the mouse homolog of human REG3A),
belonging to the antimicrobial peptides (AMPs), functions as a part of the host immune …

Type 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases
(NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β …

The gut–brain axis (GBA) is a complex bidirectional communication network connecting the
gut and brain. It involves neural, immune, and endocrine communication pathways between …

Spouses of Alzheimer's disease (AD) patients are at a higher risk of developing incidental
dementia. However, the causes and underlying mechanism of this clinical observation …

During the last decades, the gut microbiota has gained much interest in relation to human
health. Mounting evidence has shown a strict association between gut microbiota and …

Various roles of intestinal flora in the gut-brain axis response pathway have received
enormous attention because of their unique position in intestinal flora-derived metabolites …

The brain, particularly the hypothalamus and brainstem, monitors and integrates circulating
metabolic signals, including gut hormones. Gut–brain communication is also mediated by …

Interoception plays an important role in homeostatic regulation of energy intake and
metabolism. Major interoceptive pathways include gut-to-brain and adipose tissue-to brain …