Tumor microenvironment-responsive intelligent nanoplatforms for cancer theranostics
The design and development of tumor microenvironment (TME)-responsive intelligent
nanoplatforms have attracted increasing interest to enhance the therapeutic effects of drugs …
nanoplatforms have attracted increasing interest to enhance the therapeutic effects of drugs …
Liposomal drug delivery systems and anticancer drugs
Cancer is a life-threatening disease contributing to~ 3.4 million deaths worldwide. There are
various causes of cancer, such as smoking, being overweight or obese, intake of processed …
various causes of cancer, such as smoking, being overweight or obese, intake of processed …
Enzyme responsive drug delivery systems in cancer treatment
Recent technological approaches in drug delivery have attracted scientist interest for
improving therapeutic index of medicines and drug compliance. One of the powerful …
improving therapeutic index of medicines and drug compliance. One of the powerful …
Stimuliresponsive nanotherapeutics for precision drug delivery and cancer therapy
Y Qiao, J Wan, L Zhou, W Ma, Y Yang… - Wiley …, 2019 - Wiley Online Library
Cancer remains one of the world's leading causes of death. However, most conventional
chemotherapeutic drugs only show a narrow therapeutic window in patients because of their …
chemotherapeutic drugs only show a narrow therapeutic window in patients because of their …
Enzyme-responsive nanoparticles for drug release and diagnostics
Enzymes are key components of the bionanotechnology toolbox that possess exceptional
biorecognition capabilities and outstanding catalytic properties. When combined with the …
biorecognition capabilities and outstanding catalytic properties. When combined with the …
Advanced strategies in liposomal cancer therapy: problems and prospects of active and tumor specific drug release
TL Andresen, SS Jensen, K Jørgensen - Progress in lipid research, 2005 - Elsevier
Tumor specific drug delivery has become increasingly interesting in cancer therapy, as the
use of chemotherapeutics is often limited due to severe side effects. Conventional drug …
use of chemotherapeutics is often limited due to severe side effects. Conventional drug …
Phospholipase A2 superfamily in cancer
Z Peng, Y Chang, J Fan, W Ji, C Su - Cancer Letters, 2021 - Elsevier
Phospholipase A2 enzymes (PLA 2 s) comprise a superfamily that is generally divided into
six subfamilies known as cytosolic PLA 2 s (cPLA 2 s), calcium-independent PLA 2 s (iPLA 2 …
six subfamilies known as cytosolic PLA 2 s (cPLA 2 s), calcium-independent PLA 2 s (iPLA 2 …
Interfacing materials science and biology for drug carrier design
Over the last ten years, there has been considerable research interest in the development of
polymeric carriers for biomedicine. Such delivery systems have the potential to significantly …
polymeric carriers for biomedicine. Such delivery systems have the potential to significantly …
Enzyme-responsive liposomes for the delivery of anticancer drugs
F Fouladi, KJ Steffen, S Mallik - Bioconjugate Chemistry, 2017 - ACS Publications
Liposomes are nanocarriers that deliver the payloads at the target site, leading to
therapeutic drug concentrations at the diseased site and reduced toxic effects in healthy …
therapeutic drug concentrations at the diseased site and reduced toxic effects in healthy …
Receptors for a growing family of secreted phospholipases A2
G Lambeau, M Lazdunski - Trends in pharmacological sciences, 1999 - cell.com
Abstract Phospholipases A 2 (PLA 2 s) are enzymes that catalyse the hydrolysis of the sn-2
acyl bond of glycerophospholipids to produce free fatty acids and lysophospholipids …
acyl bond of glycerophospholipids to produce free fatty acids and lysophospholipids …