Triggered activation and release of liposomal prodrugs and drugs in cancer tissue by secretory phospholipase A2
TL Andresen, SS Jensen, T Kaasgaard… - Current drug …, 2005 - ingentaconnect.com
The selectivity of anticancer drugs in targeting the tumour tissue presents a major problem in
cancer treatment. In this article we review a new generation of smart liposomal nanocarriers …
cancer treatment. In this article we review a new generation of smart liposomal nanocarriers …
Leukotoxin diols from ground corncob bedding disrupt estrous cyclicity in rats and stimulate MCF-7 breast cancer cell proliferation
BM Markaverich, JR Crowley… - Environmental …, 2005 - ehp.niehs.nih.gov
Previous studies in our laboratory demonstrated that high-performance liquid
chromatography (HPLC) analysis of ground corncob bedding extracts characterized two …
chromatography (HPLC) analysis of ground corncob bedding extracts characterized two …
Cyclooxygenase and lipoxygenase inhibitors in cancer therapy
G Ara, BA Teicher - Prostaglandins, leukotrienes and essential fatty acids, 1996 - Elsevier
Tumor growth, vascularization, invasion, and metastasis require activation and/or
proliferation of specific host cells, and, perhaps, deactivation and/or suppression of others …
proliferation of specific host cells, and, perhaps, deactivation and/or suppression of others …
Potential plasma lipid biomarkers in early-stage breast cancer
N Jiang, G Zhang, L Pan, C Yan, L Zhang, Y Weng… - Biotechnology …, 2017 - Springer
Objective To find new biomarkers for early diagnosis of breast cancer. Results 847 lipid
species were identified from 78 plasma samples (37 breast cancer samples and 41 healthy …
species were identified from 78 plasma samples (37 breast cancer samples and 41 healthy …
[HTML][HTML] Arachidonic acid attenuates cell proliferation, migration and viability by a mechanism independent on calcium entry
C Cantonero, J Sánchez-Collado, JJ Lopez… - International journal of …, 2020 - mdpi.com
Arachidonic acid (AA) is a phospholipase A2 metabolite that has been reported to mediate a
plethora of cellular mechanisms involved in healthy and pathological states such as platelet …
plethora of cellular mechanisms involved in healthy and pathological states such as platelet …
Discrimination between adenocarcinoma and normal pancreatic ductal fluid by proteomic and glycomic analysis
Sensitive and specific biomarkers for pancreatic cancer are currently unavailable. The high
mortality associated with adenocarcinoma of the pancreatic epithelium justifies the broadest …
mortality associated with adenocarcinoma of the pancreatic epithelium justifies the broadest …
Plasma Levels of Phospholipase A2-IIA in Patients with Different Types of Malignancies: Prognosis and Association with Inflammatory and Coagulation Biomarkers
M Menschikowski, A Hagelgans, U Schuler… - Pathology & Oncology …, 2013 - Springer
It is well-known that the plasma level of group IIA phospholipase A 2 (sPLA 2-IIA) is
increased in patients with malignant diseases, but whether the up-regulated enzyme …
increased in patients with malignant diseases, but whether the up-regulated enzyme …
[HTML][HTML] Antitumoral effects of γCdcPLI, a PLA2 inhibitor from Crotalus durissus collilineatus via PI3K/Akt pathway on MDA-MB-231 breast cancer cell
SNC Gimenes, DS Lopes, PT Alves, FVPV Azevedo… - Scientific reports, 2017 - nature.com
Abstract Phospholipases A2 (PLA2s) overexpression is closely associated with the
malignant potential of breast cancers. Here, we showed for the first the antitumoral effects of …
malignant potential of breast cancers. Here, we showed for the first the antitumoral effects of …
[HTML][HTML] Metabolomic profiling of breast tumors using ductal fluid
L Matos Do Canto, C Marian… - International …, 2016 - spandidos-publications.com
Identification of new biomarkers for breast cancer remains critical in order to enhance early
detection of the disease and improve its prognosis. Towards this end, we performed an …
detection of the disease and improve its prognosis. Towards this end, we performed an …
Group II phospholipase A2 in human male reproductive organs and genital tumors
M Kallajoki, KA Alanen, M Nevalainen… - The …, 1998 - Wiley Online Library
Abstract BACKGROUND Group II phospholipase A2 (PLA2) is a lipolytic enzyme suggested
to play a role in inflammation and antibacterial defence. In seminal fluid, the concentration of …
to play a role in inflammation and antibacterial defence. In seminal fluid, the concentration of …