We determined the contribution of calcium-independent phospholipase A2β (iPLA2β) to
lung metastasis development following breast cancer injection into wild-type (WT) and …

Secretory phospholipase A2 (sPLA2) type IIA and X was analyzed in tumors from 22 patients
with colon adenocarcinomas in order to determine the involvement and activity of sPLA2 in …

The clinical use of anticancer lipids is severely limited by their ability to cause lysis of red
blood cells prohibiting intravenous injection. Novel delivery systems are therefore required …

Abstract Phospholipases A 2 (PLA 2 s) are enzymes responsible for mobilization of fatty
acids, including arachidonic acid (AA), from phospholipids. These enzymes are classified as …

Smart drug delivery systems that are based on environmental-responsive polymers have
been developed to specifically deliver cargos to desired disease sites and controlled drug …

Lipid-based drug carriers are an attractive option to solubilise poorly water soluble
therapeutics. Previously, we reported that the digestion of a short tail PC lipid (2C6PC) by …

Imaging of individual lipid vesicles is used to track single-enzyme kinetics of phospholipid
hydrolysis. The method is employed to quantify the catalytic activity of phospholipase A2 …

Previous studies have indicated that phospholipase A2 (PLA2) may be associated with
tumorigenesis in human tissues. The present study aimed to investigate the association …

Background. Five products of human breast carcinoma cells, including membrane-
associated phospholipase A2 (M-PLA2), polymorphonuclear leukocyte elastase (PMN-E) …

Phospholipase A2 (PLA2) is an enzyme that catalyzes the hydrolysis of membrane
phospholipids. This article reviews the source and structure of PLA2, the involvement of the …