Infantile spasms: a US consensus report

JM Pellock, R Hrachovy, S Shinnar, TZ Baram… - …, 2010 - Wiley Online Library
The diagnosis, evaluation, and management of infantile spasms (IS) continue to pose
significant challenges to the treating physician. Although an evidence‐based practice …

The epidemiology of the epilepsies in children

LD Cowan - Mental retardation and developmental disabilities …, 2002 - Wiley Online Library
The epilepsies are a heterogeneous collection of neurological conditions and syndromes
characterized by recurrent, unprovoked, paroxysmal seizure activity. There are several types …

Long‐term cognitive outcomes of a cohort of children with cryptogenic infantile spasms treated with high‐dose adrenocorticotropic hormone

S Kivity, P Lerman, R Ariel, Y Danziger, M Mimouni… - …, 2004 - Wiley Online Library
Purpose: To evaluate the outcome of children with cryptogenic infantile spasms treated with
high‐dose synthetic adrenocorticotropic hormone (ACTH) and the relation between early …

The epidemiology and natural history of infantile spasms

LD Cowan, LS Hudson - Journal of child neurology, 1991 - journals.sagepub.com
Few population-based studies of infantile spasms have been done, and most reports have
not included comparison groups. In spite of these limitations, this review attempts to …

The descriptive epidemiology of infantile spasms among Atlanta children

E Trevathan, CC Murphy, M Yeargin‐Allsopp - Epilepsia, 1999 - Wiley Online Library
Purpose: To determine the population‐based epidemiology of infantile spasms (IS) among
Atlanta children. Methods: By using data from a cross‐sectional, population‐based …

Developmental outcomes in children receiving resection surgery for medically intractable infantile spasms

RF Asarnow, C LoPresti, D Guthrie… - … Medicine & Child …, 1997 - Wiley Online Library
Two‐year postsurgical developmental outcomes were assessed in 24 children with infantile
spasms who underwent resective surgery. The mean age of onset of infantile spasms was …

Statistical mapping of ictal high‐frequency oscillations in epileptic spasms

H Nariai, T Nagasawa, C Juhász, S Sood… - …, 2011 - Wiley Online Library
Purpose: We assessed 636 epileptic spasms seen in 11 children (median 44 spasms per
child) and determined the spatial and temporal characteristics of ictal high‐frequency …

Pathogenesis of infantile spasms: a model based on developmental desynchronization

JD Frost Jr, RA Hrachovy - Journal of Clinical Neurophysiology, 2005 - journals.lww.com
Infantile spasms is a severe epileptic encephalopathy of infancy. The fundamental cause is
unknown, although a number of predisposing conditions are recognized. In this article, the …

ACTH treatment of infantile spasms: mechanisms of its effects in modulation of neuronal excitability

KL Brunson, S Avishai-Eliner, TZ Baram - International review of …, 2002 - Elsevier
The efficacy of ACTH, particularly in high doses, for rapid and complete elimination of
infantile spasms (IS) has been demonstrated in prospective controlled studies. However, the …

West syndrome: etiological and prognostic aspects

K Watanabe - Brain and Development, 1998 - Elsevier
West syndrome is a multi-etiological condition. Recent progress in perinatal medicine and
the recent development of new neuroimaging techniques may have changed the etiological …