The identification of secreted proteins that are differentially expressed between non-
neoplastic and esophageal squamous cell carcinoma (ESCC) cells can provide potential …

Curcumin is a natural active ingredient from traditional Chinese medicine (TCM) that has
multi-target characteristics to exert extensive pharmacological activities and thus has been …

Background: High cathepsin D has been associated with poor prognosis in breast cancer;
however, the results of many studies are controversial. Here, we assessed the association …

Cathepsin D (CatD), a lysosomal aspartic protease, plays an essential role in tumor
progression and apoptosis. However, the function of CatD in cell death is not yet fully …

Although previous studies have reported the effects of extensive subculturing on
proliferation rates and osteogenic potential of human mesenchymal stem cells (hMSCs), the …

The aspartic protease cathepsin-D (cath-D) is overexpressed by human epithelial breast
cancer cells and is closely correlated with poor prognosis in breast cancer. The adipocyte is …

Overexpression and secretion of the enzymes cathepsin D (CathD) and cathepsin L (CathL)
is associated with metastasis in several human cancers. As a superfamily, extracellularly …

The human olfactomedin 4 gene (OLFM4) encodes an olfactomedin-related glycoprotein.
OLFM4 is normally expressed in a limited number of tissues, including the prostate, but its …

This study aimed at characterizing the impact of type 2 diabetes mellitus (T2 DM) on the
bone marrow mesenchymal stem cell (BMMSC) secretome and angiogenic properties …

Expression and secretion of procathepsin D (pCD) increases proliferation, metastasis and
progression of breast cancer but the structural moiety by which pCD exerts these effects is …